Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KXB63238.1Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; KEGG: lba:Lebu_0558 1.3e-149 nicotinate-nucleotide/dimethylbenzimidazole phosphoribosyl transferase; K00768 nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Psort location: Cytoplasmic, score: 9.97. (388 aa)    
Predicted Functional Partners:
KXB67942.1
Putative adenosylcobalamin biosynthesis protein CobU; KEGG: lba:Lebu_0472 1.2e-82 cobalbumin biosynthesis protein; K02231 adenosylcobinamide kinase / adenosylcobinamide-phosphate guanylyltransferase; Psort location: Cytoplasmic, score: 9.26.
  
 0.988
KXB63124.1
KEGG: lba:Lebu_1978 1.2e-82 phosphoglycerate mutase; K15634 probable phosphoglycerate mutase; Psort location: Cytoplasmic, score: 9.97.
 
 
 0.957
cobS
adenosylcobinamide-GDP ribazoletransferase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
 
 
 0.946
cbiA
Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
  
 0.938
KXB66005.1
KEGG: lba:Lebu_0267 2.5e-84 phosphoglycerate mutase; K02226 alpha-ribazole phosphatase; Psort location: Cytoplasmic, score: 8.96.
  
 
 0.926
cobQ
Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
 
  
 0.901
cobD
Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
 
  
 0.845
KXB60911.1
Aminotransferase, class I/II; KEGG: lba:Lebu_0041 1.8e-186 threonine-phosphate decarboxylase; K04720 threonine-phosphate decarboxylase; Psort location: Cytoplasmic, score: 9.97.
 
  
 0.605
hemL
Glutamate-1-semialdehyde-2,1-aminomutase; KEGG: lba:Lebu_0559 1.6e-208 glutamate-1-semialdehyde aminotransferase; K01845 glutamate-1-semialdehyde 2,1-aminomutase; Psort location: Cytoplasmic, score: 9.97.
       0.549
KXB60893.1
KEGG: lba:Lebu_0096 5.2e-84 precorrin-8X methylmutase CbiC/CobH; K06042 precorrin-8X methylmutase; Psort location: Cytoplasmic, score: 8.96.
 
  
 0.535
Your Current Organism:
Leptotrichia wadei
NCBI taxonomy Id: 157687
Other names: CCUG 47505, CIP 107918, DSM 19758, JCM 16777, L. wadei, Leptotrichia sp. LB16, Leptotrichia wadei Eribe et al. 2004, strain LB 16
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