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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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leuC3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (472 aa)    
Predicted Functional Partners:
leuD
3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.
 0.999
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
 0.997
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
 
 
 0.992
KXB64520.1
KEGG: lba:Lebu_0381 0. pyruvate ferredoxin/flavodoxin oxidoreductase; K03737 putative pyruvate-flavodoxin oxidoreductase; Psort location: Cytoplasmic, score: 8.96.
  
 0.877
KXB68816.1
Putative D-lactate dehydrogenase; KEGG: lba:Lebu_0987 1.7e-174 NAD-binding D-isomer specific 2-hydroxyacid dehydrogenase; K03778 D-lactate dehydrogenase; Psort location: Cytoplasmic, score: 9.97.
    
 0.823
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
 
  
 0.822
ilvD
KEGG: lba:Lebu_1760 1.1e-273 dihydroxy-acid dehydratase; K01687 dihydroxy-acid dehydratase; Psort location: Cytoplasmic, score: 9.97; Belongs to the IlvD/Edd family.
 
  
 0.815
KXB68615.1
KEGG: lba:Lebu_1756 3.6e-69 acetolactate synthase small subunit; K01653 acetolactate synthase I/III small subunit; Psort location: Cytoplasmic, score: 9.97.
  
  
 0.812
KXB59849.1
Pyruvate kinase; KEGG: lba:Lebu_0874 2.9e-234 pyruvate kinase; K00873 pyruvate kinase; Psort location: Cytoplasmic, score: 9.97.
    
  0.803
KXB67972.1
Putative TPP-dependent acetoin dehydrogenase complex, E1 component, alpha subunit; KEGG: lba:Lebu_0541 2.7e-151 pyruvate dehydrogenase; K00161 pyruvate dehydrogenase E1 component subunit alpha; Psort location: Cytoplasmic, score: 9.97.
     
  0.800
Your Current Organism:
Leptotrichia wadei
NCBI taxonomy Id: 157687
Other names: CCUG 47505, CIP 107918, DSM 19758, JCM 16777, L. wadei, Leptotrichia sp. LB16, Leptotrichia wadei Eribe et al. 2004, strain LB 16
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