Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (267 aa)    
Predicted Functional Partners:
proB
Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
 
 
 0.753
proA
Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
 
 
 0.723
KXB61558.1
KEGG: aur:HMPREF9243_0416 4.8e-42 ATP:cob(I)alamin adenosyltransferase; Psort location: Cytoplasmic, score: 9.97.
       0.723
KXB69661.1
Putative glutamate synthase [NADPH], large subunit; KEGG: str:Sterm_2340 0. glutamate synthase K00265; Psort location: Cytoplasmic, score: 9.26.
     
 0.518
GlcK
Putative glucokinase; KEGG: lba:Lebu_1037 1.8e-154 ROK family glucokinase; K00845 glucokinase; Psort location: Cytoplasmic, score: 9.97.
     
 0.517
aroK
Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
 
   
 0.474
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
  
  
 0.426
KXB61408.1
KEGG: lba:Lebu_1538 0. phosphoribosylformylglycinamidine synthase; K01952 phosphoribosylformylglycinamidine synthase; Psort location: Cytoplasmic, score: 9.94.
     
 0.412
KXB61557.1
Hypothetical protein.
       0.411
SerA
KEGG: lba:Lebu_1043 2.7e-261 D-3-phosphoglycerate dehydrogenase; K00058 D-3-phosphoglycerate dehydrogenase; Psort location: Cytoplasmic, score: 9.97; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
     
 0.403
Your Current Organism:
Leptotrichia wadei
NCBI taxonomy Id: 157687
Other names: CCUG 47505, CIP 107918, DSM 19758, JCM 16777, L. wadei, Leptotrichia sp. LB16, Leptotrichia wadei Eribe et al. 2004, strain LB 16
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