Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DnaEKEGG: lba:Lebu_0463 0. DNA polymerase III subunit alpha; K02337 DNA polymerase III subunit alpha; Psort location: Cytoplasmic, score: 9.97. (1185 aa)    
Predicted Functional Partners:
DnaN
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 
 0.990
KXB67231.1
KEGG: lba:Lebu_1817 1.2e-157 DNA polymerase III subunit delta; K02340 DNA polymerase III subunit delta; Psort location: Cytoplasmic, score: 8.96.
  
 0.989
dnaX
DNA polymerase III, subunit gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
 
 0.987
KXB66071.1
Hypothetical protein; KEGG: lba:Lebu_2064 7.9e-152 ATPase; K02341 DNA polymerase III subunit delta'; Psort location: Cytoplasmic, score: 8.96.
 
 0.987
KXB64645.1
Exonuclease; KEGG: lba:Lebu_1206 8.1e-111 exonuclease RNase T and DNA polymerase III; K02342 DNA polymerase III subunit epsilon; Psort location: Cytoplasmic, score: 8.96.
   
 0.984
polC
DNA polymerase III, alpha subunit; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
    
0.926
KXB70016.1
KEGG: shn:Shewana3_3590 8.5e-13 single-strand binding protein K03111.
 
 
 
 0.900
KXB61014.1
Hypothetical protein; KEGG: fnu:FN0522 0.0026 exonuclease SbcC K03546; Psort location: Cytoplasmic, score: 8.96.
       0.701
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
   
 0.699
KXB61016.1
Cof-like hydrolase; KEGG: ppo:PPM_1251 7.7e-35 yxeH; HMP-PP phosphatase K07024; Psort location: Cytoplasmic, score: 8.96.
       0.685
Your Current Organism:
Leptotrichia wadei
NCBI taxonomy Id: 157687
Other names: CCUG 47505, CIP 107918, DSM 19758, JCM 16777, L. wadei, Leptotrichia sp. LB16, Leptotrichia wadei Eribe et al. 2004, strain LB 16
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