Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KXB61030.1Citrate lyase ligase domain protein; KEGG: lba:Lebu_1786 3.0e-81 cytidyltransferase-related domain-containing protein; K00952 nicotinamide-nucleotide adenylyltransferase; Psort location: Cytoplasmic, score: 8.96. (178 aa)    
Predicted Functional Partners:
NadE
NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
  
 
 0.968
pncB
Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family.
    
 0.967
KXB67926.1
Putative NAD-dependent deacetylase; KEGG: lba:Lebu_2235 1.5e-118 silent information regulator protein Sir2; K12410 NAD-dependent deacetylase; Psort location: Cytoplasmic, score: 9.97.
  
 
  0.941
KXB69982.1
KEGG: hso:HS_0087 1.9e-70 nadR; nicotinamide-nucleotide adenylyltransferase K06211; Psort location: Cytoplasmic, score: 8.96.
  
 
 0.919
KXB69220.1
KEGG: yen:YE0580 1.6e-82 b4390; nicotinamide-nucleotide adenylyltransferase K06211; Psort location: Cytoplasmic, score: 8.96.
  
 
 0.919
nadK
Putative inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
    
 0.919
KXB69568.1
KEGG: lba:Lebu_1965 1.7e-275 NAD pyrophosphatase/5'-nucleotidase NadN; K01081 5'-nucleotidase; Psort location: Periplasmic, score: 9.76; Belongs to the 5'-nucleotidase family.
     
 0.902
cysS
cysteine--tRNA ligase; KEGG: lba:Lebu_2108 5.2e-251 cysteinyl-tRNA synthetase; K01883 cysteinyl-tRNA synthetase; Psort location: Cytoplasmic, score: 9.97; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
    0.402
Your Current Organism:
Leptotrichia wadei
NCBI taxonomy Id: 157687
Other names: CCUG 47505, CIP 107918, DSM 19758, JCM 16777, L. wadei, Leptotrichia sp. LB16, Leptotrichia wadei Eribe et al. 2004, strain LB 16
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