STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TrxA_2Hypothetical protein; KEGG: suq:HMPREF0772_12088 9.0e-09 trxA; thioredoxin K03671. (79 aa)    
Predicted Functional Partners:
KXB60140.1
Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
  
 
 0.750
KXB67945.1
KEGG: lba:Lebu_1955 2.4e-150 thioredoxin reductase; K00384 thioredoxin reductase (NADPH); Psort location: Cytoplasmic, score: 9.97.
  
 
 0.662
groL
Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
   
 
 0.644
LpdA
Dihydrolipoyl dehydrogenase; KEGG: lba:Lebu_0545 2.8e-243 dihydrolipoamide dehydrogenase; K00382 dihydrolipoamide dehydrogenase; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.610
NrdI
nrdI protein; KEGG: sax:USA300HOU_0754 9.5e-14 nrdI; ribonucleotide reductase stimulatory protein K03647; Belongs to the NrdI family.
  
  
 0.526
KXB69661.1
Putative glutamate synthase [NADPH], large subunit; KEGG: str:Sterm_2340 0. glutamate synthase K00265; Psort location: Cytoplasmic, score: 9.26.
    
 
 0.499
KXB60137.1
Hypothetical protein.
       0.493
MetH
5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
     
 0.439
KXB69246.1
Putative low molecular weight protein-tyrosine-phosphatase PtpA; KEGG: lba:Lebu_2236 8.3e-54 protein tyrosine phosphatase; K01104 protein-tyrosine phosphatase; Psort location: Cytoplasmic, score: 8.96; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
  
 
 0.438
msrA-2
Peptide-methionine (S)-S-oxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
  
  
 0.426
Your Current Organism:
Leptotrichia wadei
NCBI taxonomy Id: 157687
Other names: CCUG 47505, CIP 107918, DSM 19758, JCM 16777, L. wadei, Leptotrichia sp. LB16, Leptotrichia wadei Eribe et al. 2004, strain LB 16
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