| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KXB59887.1 | KXB59888.1 | HMPREF3180_02116 | HMPREF3180_02117 | KEGG: lba:Lebu_1559 5.1e-102 riboflavin synthase subunit alpha; K00793 riboflavin synthase; Psort location: Cytoplasmic, score: 9.97. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.989 |
| KXB59887.1 | ribBA | HMPREF3180_02116 | HMPREF3180_02115 | KEGG: lba:Lebu_1559 5.1e-102 riboflavin synthase subunit alpha; K00793 riboflavin synthase; Psort location: Cytoplasmic, score: 9.97. | 3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.999 |
| KXB59887.1 | ribH | HMPREF3180_02116 | HMPREF3180_02118 | KEGG: lba:Lebu_1559 5.1e-102 riboflavin synthase subunit alpha; K00793 riboflavin synthase; Psort location: Cytoplasmic, score: 9.97. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.999 |
| KXB59888.1 | KXB59887.1 | HMPREF3180_02117 | HMPREF3180_02116 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | KEGG: lba:Lebu_1559 5.1e-102 riboflavin synthase subunit alpha; K00793 riboflavin synthase; Psort location: Cytoplasmic, score: 9.97. | 0.989 |
| KXB59888.1 | KXB63647.1 | HMPREF3180_02117 | HMPREF3180_01534 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | KEGG: lba:Lebu_0127 1.8e-97 biotin--acetyl-CoA-carboxylase ligase; K03524 BirA family transcriptional regulator, biotin operon repressor / biotin-[acetyl-CoA-carboxylase] ligase; Psort location: Cytoplasmic, score: 9.97. | 0.426 |
| KXB59888.1 | KXB64189.1 | HMPREF3180_02117 | HMPREF3180_01453 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Universal bacterial protein YeaZ; KEGG: fnu:FN0928 5.1e-22 O-sialoglycoprotein endopeptidase K01409; Psort location: Cytoplasmic, score: 8.96. | 0.472 |
| KXB59888.1 | KXB64392.1 | HMPREF3180_02117 | HMPREF3180_01419 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | biotin--[acetyl-CoA-carboxylase] ligase; KEGG: fnu:FN1921 1.7e-53 biotin operon repressor K03524; Psort location: Cytoplasmic, score: 9.97. | 0.426 |
| KXB59888.1 | guaA | HMPREF3180_02117 | HMPREF3180_01046 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP. | 0.427 |
| KXB59888.1 | hisI | HMPREF3180_02117 | HMPREF3180_01296 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | KEGG: lba:Lebu_1219 8.4e-109 phosphoribosyl-ATP diphosphatase; K11755 phosphoribosyl-ATP pyrophosphohydrolase / phosphoribosyl-AMP cyclohydrolase; Psort location: Cytoplasmic, score: 9.97; In the N-terminal section; belongs to the PRA-CH family. | 0.931 |
| KXB59888.1 | metG | HMPREF3180_02117 | HMPREF3180_00246 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.416 |
| KXB59888.1 | ribBA | HMPREF3180_02117 | HMPREF3180_02115 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.997 |
| KXB59888.1 | ribH | HMPREF3180_02117 | HMPREF3180_02118 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.923 |
| KXB59888.1 | tdk | HMPREF3180_02117 | HMPREF3180_00033 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Thymidine kinase; KEGG: lba:Lebu_1391 1.4e-179 thymidine kinase; K00857 thymidine kinase; Psort location: Cytoplasmic, score: 9.97. | 0.416 |
| KXB63647.1 | KXB59888.1 | HMPREF3180_01534 | HMPREF3180_02117 | KEGG: lba:Lebu_0127 1.8e-97 biotin--acetyl-CoA-carboxylase ligase; K03524 BirA family transcriptional regulator, biotin operon repressor / biotin-[acetyl-CoA-carboxylase] ligase; Psort location: Cytoplasmic, score: 9.97. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.426 |
| KXB63647.1 | KXB64189.1 | HMPREF3180_01534 | HMPREF3180_01453 | KEGG: lba:Lebu_0127 1.8e-97 biotin--acetyl-CoA-carboxylase ligase; K03524 BirA family transcriptional regulator, biotin operon repressor / biotin-[acetyl-CoA-carboxylase] ligase; Psort location: Cytoplasmic, score: 9.97. | Universal bacterial protein YeaZ; KEGG: fnu:FN0928 5.1e-22 O-sialoglycoprotein endopeptidase K01409; Psort location: Cytoplasmic, score: 8.96. | 0.407 |
| KXB63647.1 | KXB64392.1 | HMPREF3180_01534 | HMPREF3180_01419 | KEGG: lba:Lebu_0127 1.8e-97 biotin--acetyl-CoA-carboxylase ligase; K03524 BirA family transcriptional regulator, biotin operon repressor / biotin-[acetyl-CoA-carboxylase] ligase; Psort location: Cytoplasmic, score: 9.97. | biotin--[acetyl-CoA-carboxylase] ligase; KEGG: fnu:FN1921 1.7e-53 biotin operon repressor K03524; Psort location: Cytoplasmic, score: 9.97. | 0.914 |
| KXB63647.1 | ribBA | HMPREF3180_01534 | HMPREF3180_02115 | KEGG: lba:Lebu_0127 1.8e-97 biotin--acetyl-CoA-carboxylase ligase; K03524 BirA family transcriptional regulator, biotin operon repressor / biotin-[acetyl-CoA-carboxylase] ligase; Psort location: Cytoplasmic, score: 9.97. | 3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.412 |
| KXB64189.1 | KXB59888.1 | HMPREF3180_01453 | HMPREF3180_02117 | Universal bacterial protein YeaZ; KEGG: fnu:FN0928 5.1e-22 O-sialoglycoprotein endopeptidase K01409; Psort location: Cytoplasmic, score: 8.96. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.472 |
| KXB64189.1 | KXB63647.1 | HMPREF3180_01453 | HMPREF3180_01534 | Universal bacterial protein YeaZ; KEGG: fnu:FN0928 5.1e-22 O-sialoglycoprotein endopeptidase K01409; Psort location: Cytoplasmic, score: 8.96. | KEGG: lba:Lebu_0127 1.8e-97 biotin--acetyl-CoA-carboxylase ligase; K03524 BirA family transcriptional regulator, biotin operon repressor / biotin-[acetyl-CoA-carboxylase] ligase; Psort location: Cytoplasmic, score: 9.97. | 0.407 |
| KXB64189.1 | KXB64392.1 | HMPREF3180_01453 | HMPREF3180_01419 | Universal bacterial protein YeaZ; KEGG: fnu:FN0928 5.1e-22 O-sialoglycoprotein endopeptidase K01409; Psort location: Cytoplasmic, score: 8.96. | biotin--[acetyl-CoA-carboxylase] ligase; KEGG: fnu:FN1921 1.7e-53 biotin operon repressor K03524; Psort location: Cytoplasmic, score: 9.97. | 0.407 |