Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
pyrFOrotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (246 aa)    
Predicted Functional Partners:
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
 
 0.998
KXB59907.1
Amidohydrolase family protein; KEGG: lba:Lebu_0770 3.1e-198 dihydroorotase; K01465 dihydroorotase; Psort location: Cytoplasmic, score: 9.97.
 
  
 0.953
pyrB
KEGG: lba:Lebu_0766 2.1e-151 aspartate carbamoyltransferase; K00609 aspartate carbamoyltransferase catalytic subunit; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
  
  
 0.951
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
  
 
 0.934
pyrD
Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate.
 
  
 0.929
pyrH
UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
   
 
 0.926
udk
Uridine kinase; KEGG: lba:Lebu_1122 1.9e-102 uridine kinase; K00876 uridine kinase; Psort location: Cytoplasmic, score: 9.97.
   
 
 0.908
carB
KEGG: lba:Lebu_1617 0. carB; carbamoyl phosphate synthase large subunit; K01955 carbamoyl-phosphate synthase large subunit; Psort location: Cytoplasmic, score: 9.97.
  
  
 0.907
KXB69568.1
KEGG: lba:Lebu_1965 1.7e-275 NAD pyrophosphatase/5'-nucleotidase NadN; K01081 5'-nucleotidase; Psort location: Periplasmic, score: 9.76; Belongs to the 5'-nucleotidase family.
    
 0.900
AsrB
KEGG: cby:CLM_1109 7.6e-76 asrB; anaerobic sulfite reductase subunit B; Psort location: Cytoplasmic, score: 9.97.
  
  
 0.894
Your Current Organism:
Leptotrichia wadei
NCBI taxonomy Id: 157687
Other names: CCUG 47505, CIP 107918, DSM 19758, JCM 16777, L. wadei, Leptotrichia sp. LB16, Leptotrichia wadei Eribe et al. 2004, strain LB 16
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