Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene Fusion
Co-occurrence
Co-expression
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[Homology]
Score
glyQglycine--tRNA ligase, alpha subunit; KEGG: lba:Lebu_0362 3.5e-158 glyQ; glycyl-tRNA synthetase subunit alpha; K01878 glycyl-tRNA synthetase alpha chain; Psort location: Cytoplasmic, score: 9.97. (291 aa)    
Predicted Functional Partners:
glyS
KEGG: lba:Lebu_0365 0. glycyl-tRNA synthetase subunit beta; K01879 glycyl-tRNA synthetase beta chain; Psort location: Cytoplasmic, score: 9.97.
 0.999
lspA
Signal peptidase II; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.
       0.806
ileS
isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
  
  
 0.789
KXB59292.1
Hypothetical protein; KEGG: bcc:BCc_164 0.00011 lepB; hypothetical protein K03100; Psort location: CytoplasmicMembrane, score: 10.00.
       0.773
hisS
histidine--tRNA ligase; KEGG: lba:Lebu_1869 4.4e-190 histidyl-tRNA synthetase; K01892 histidyl-tRNA synthetase; Psort location: Cytoplasmic, score: 10.00.
  
  
 0.635
KXB59294.1
Hypothetical protein; KEGG: edi:EDI_048910 2.7e-06 intracellular protein transport protein USO1; Psort location: Cytoplasmic, score: 8.96.
       0.632
KXB59295.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.96.
       0.625
alaS
alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
   
  
 0.591
pheS
KEGG: lba:Lebu_2182 5.8e-165 phenylalanyl-tRNA synthetase subunit alpha; K01889 phenylalanyl-tRNA synthetase alpha chain; Psort location: Cytoplasmic, score: 10.00.
   
  
 0.555
metG
methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
  
 0.551
Your Current Organism:
Leptotrichia wadei
NCBI taxonomy Id: 157687
Other names: CCUG 47505, CIP 107918, DSM 19758, JCM 16777, L. wadei, Leptotrichia sp. LB16, Leptotrichia wadei Eribe et al. 2004, strain LB 16
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