node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KMM36715.1 | KMM38337.1 | AB986_12275 | AB986_03230 | Histidinol phosphate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.867 |
KMM36715.1 | hisA | AB986_12275 | AB986_13940 | Histidinol phosphate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.871 |
KMM36715.1 | hisB | AB986_12275 | AB986_13930 | Histidinol phosphate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Imidazoleglycerol-phosphate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.958 |
KMM36715.1 | hisD | AB986_12275 | AB986_13925 | Histidinol phosphate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.955 |
KMM36715.1 | hisF | AB986_12275 | AB986_13945 | Histidinol phosphate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Imidazole glycerol phosphate synthase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.929 |
KMM36715.1 | hisG | AB986_12275 | AB986_13920 | Histidinol phosphate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. | 0.870 |
KMM36715.1 | hisH | AB986_12275 | AB986_13935 | Histidinol phosphate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Imidazole glycerol phosphate synthase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.936 |
KMM36715.1 | hisI | AB986_12275 | AB986_13950 | Histidinol phosphate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | phosphoribosyl-ATP pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology; In the N-terminal section; belongs to the PRA-CH family. | 0.997 |
KMM36715.1 | hisZ | AB986_12275 | AB986_13915 | Histidinol phosphate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP phosphoribosyltransferase; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine. | 0.840 |
KMM38337.1 | KMM36715.1 | AB986_03230 | AB986_12275 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Histidinol phosphate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.867 |
KMM38337.1 | hisA | AB986_03230 | AB986_13940 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.891 |
KMM38337.1 | hisC | AB986_03230 | AB986_02225 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Histidinol-phosphate aminotransferase; Catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.867 |
KMM38337.1 | hisD | AB986_03230 | AB986_13925 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.911 |
KMM38337.1 | hisF | AB986_03230 | AB986_13945 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Imidazole glycerol phosphate synthase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.911 |
KMM38337.1 | hisG | AB986_03230 | AB986_13920 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. | 0.850 |
KMM38337.1 | hisH | AB986_03230 | AB986_13935 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Imidazole glycerol phosphate synthase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.911 |
KMM38337.1 | hisI | AB986_03230 | AB986_13950 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | phosphoribosyl-ATP pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology; In the N-terminal section; belongs to the PRA-CH family. | 0.999 |
KMM38337.1 | hisZ | AB986_03230 | AB986_13915 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP phosphoribosyltransferase; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine. | 0.850 |
hisA | KMM36715.1 | AB986_13940 | AB986_12275 | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Histidinol phosphate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.871 |
hisA | KMM38337.1 | AB986_13940 | AB986_03230 | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.891 |