STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AIZ34063.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (294 aa)    
Predicted Functional Partners:
AIZ34064.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.773
nfuA
Amino acid ABC transporter substrate-binding protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.
  
  
 0.667
iscS
Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
  
  
 0.636
AIZ33246.1
Class V aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.636
AIZ31684.1
Scaffolding protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
  
  
 0.583
AIZ31645.1
Dihydropteridine reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.528
AIZ35036.1
Rubredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.506
AIZ34974.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.502
AIZ34065.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.501
thiI
tRNA s(4)U8 sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
  
  
 0.483
Your Current Organism:
Pseudomonas parafulva
NCBI taxonomy Id: 157782
Other names: AJ 2129, CIP 107617, DSM 17004, IFO 16636, JCM 11244, NBRC 16636, NRIC 0501, P. parafulva, Pseudomonas parafulva Uchino et al. 2002, strain CB-1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.