STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AIZ34698.1Ammonia channel protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (444 aa)    
Predicted Functional Partners:
AIZ34699.1
Nitrogen regulatory protein P-II 1; Indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
gltB
Catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.805
AIZ35307.1
Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.743
AIZ33620.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.737
AIZ35220.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.732
glnD
protein-PII uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
 
   
 0.560
cysG
Sirohydrochlorin ferrochelatase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
 
   
 0.547
AIZ35036.1
Rubredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.520
aspA-2
Aspartate ammonia-lyase; Catalyzes the formation of fumarate from aspartate; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.518
AIZ33685.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.513
Your Current Organism:
Pseudomonas parafulva
NCBI taxonomy Id: 157782
Other names: AJ 2129, CIP 107617, DSM 17004, IFO 16636, JCM 11244, NBRC 16636, NRIC 0501, P. parafulva, Pseudomonas parafulva Uchino et al. 2002, strain CB-1
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