node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KQL50593.1 | KQL51233.1 | AN964_23370 | AN964_19765 | Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S14 family. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.551 |
KQL50593.1 | dnaJ | AN964_23370 | AN964_08305 | Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S14 family. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.517 |
KQL50593.1 | dnaK | AN964_23370 | AN964_08300 | Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S14 family. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.648 |
KQL50593.1 | groEL | AN964_23370 | AN964_18530 | Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S14 family. | Molecular chaperone GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.579 |
KQL50593.1 | grpE | AN964_23370 | AN964_08295 | Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S14 family. | Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] | 0.620 |
KQL50593.1 | hrcA | AN964_23370 | AN964_08290 | Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S14 family. | HrcA family transcriptional regulator; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.764 |
KQL51233.1 | KQL50593.1 | AN964_19765 | AN964_23370 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S14 family. | 0.551 |
KQL51233.1 | KQL55507.1 | AN964_19765 | AN964_14455 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Translocation-enhancing protein TepA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.551 |
KQL51233.1 | clpP | AN964_19765 | AN964_05915 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Clp protease; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.551 |
KQL51233.1 | clpP-2 | AN964_19765 | AN964_10425 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Clp protease; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.551 |
KQL51233.1 | dnaJ | AN964_19765 | AN964_08305 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.994 |
KQL51233.1 | groEL | AN964_19765 | AN964_18530 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molecular chaperone GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.930 |
KQL51233.1 | grpE | AN964_19765 | AN964_08295 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] | 0.984 |
KQL51233.1 | hrcA | AN964_19765 | AN964_08290 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | HrcA family transcriptional regulator; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.820 |
KQL55507.1 | KQL51233.1 | AN964_14455 | AN964_19765 | Translocation-enhancing protein TepA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.551 |
KQL55507.1 | dnaJ | AN964_14455 | AN964_08305 | Translocation-enhancing protein TepA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.552 |
KQL55507.1 | dnaK | AN964_14455 | AN964_08300 | Translocation-enhancing protein TepA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.617 |
KQL55507.1 | groEL | AN964_14455 | AN964_18530 | Translocation-enhancing protein TepA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molecular chaperone GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.610 |
KQL55507.1 | grpE | AN964_14455 | AN964_08295 | Translocation-enhancing protein TepA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] | 0.646 |
KQL55507.1 | hrcA | AN964_14455 | AN964_08290 | Translocation-enhancing protein TepA; Derived by automated computational analysis using gene prediction method: Protein Homology. | HrcA family transcriptional regulator; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.771 |