STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KQL54711.1Peptidase; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. (308 aa)    
Predicted Functional Partners:
KQL51387.1
Stage II sporulation protein E; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.953
spoIIAB
Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
  
 0.925
KQL54710.1
Sporulation sigma factor SigE; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
  
 0.867
KQL51566.1
Stage II sporulation protein R; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.865
KQL54709.1
RNA polymerase sigma-G factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
  
 0.857
KQL53639.1
Stage II sporulation protein M; Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane.
  
  
 0.821
KQL54740.1
Sporulation integral membrane protein YlbJ; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.808
KQL53507.1
Stage IV sporulation protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.803
KQL54708.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.798
KQL53575.1
Stage III sporulation protein AA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.788
Your Current Organism:
Bacillus shackletonii
NCBI taxonomy Id: 157838
Other names: B. shackletonii, Bacillus shackletonii Logan et al. 2004, CIP 107762, LMG 18435, LMG:18435, bacterium LMG 18435, strain Logan B1724, strain SSI024
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