STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDR49691.1Peroxiredoxin. (179 aa)    
Predicted Functional Partners:
SDR49686.1
Cytochrome c biogenesis protein CcdA.
 
 0.999
msrA
Peptide-methionine (S)-S-oxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
   
 0.983
msrA-2
Peptide-methionine (S)-S-oxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
   
 0.983
SDQ59828.1
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.
   
 0.973
SDR61421.1
2,4-dienoyl-CoA reductase.
  
 0.967
SDR54415.1
Cytochrome c oxidase subunit 2.
   
 
 0.965
SDR60464.1
Cytochrome c oxidase subunit 2.
  
 
 0.953
SDQ31991.1
Dihydrolipoamide dehydrogenase.
  
 0.952
SDQ84319.1
Cytochrome c oxidase subunit 2; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
 
 
 
 0.951
dsbD
Thiol:disulfide interchange protein DsbD; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily.
  
 
 0.948
Your Current Organism:
Paraburkholderia tuberum
NCBI taxonomy Id: 157910
Other names: Burkholderia sp. WSM4174, Burkholderia sp. WSM4175, Burkholderia sp. WSM4176, Burkholderia sp. WSM4177, Burkholderia sp. WSM4179, Burkholderia sp. WSM4180, Burkholderia tuberum, Burkholderia tuberum Vandamme et al. 2003, CCUG 47178, CIP 108238, DSM 18489, LMG 21444, LMG:21444, P. tuberum, Paraburkholderia tuberum (Vandamme et al. 2003) Sawana et al. 2015, strain STM678
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