STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pdhAPyruvate dehydrogenase (Acetyl-transferring) E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (366 aa)    
Predicted Functional Partners:
AKS42171.1
Pyruvate dehydrogenase E1 component (Beta subunit) oxidoreductase protein; Pfam:pfam02779 Transketolase, pyrimidine binding domain.
 0.999
AKS42971.1
Dihydrolipoamide dehydrogenase; Pfam:pfam07992 Pyridine nucleotide-disulphide oxidoreductase.
 0.999
AKS42172.1
Branched-chain alpha-keto acid dehydrogenase subunit E2; Pfam:pfam00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain).
 
 0.998
AKS42975.1
Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 0.992
AKS41899.1
Dihydrolipoamide dehydrogenase; Pfam:pfam07992 Pyridine nucleotide-disulphide oxidoreductase.
 
 0.979
WM2015_48
Dihydrolipoamide dehydrogenase; Pfam:pfam07992 Pyridine nucleotide-disulphide oxidoreductase.
 
 0.975
AKS42979.1
Malic enzyme; Pfam:pfam01515 Phosphate acetyl/butaryl transferase; Belongs to the malic enzymes family.
  
 
 0.960
AKS41711.1
MFS transporter; Pfam:pfam02780 Transketolase, C-terminal domain.
 
0.956
AKS41900.1
Dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
 
 0.938
AKS41911.1
Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
    
 0.918
Your Current Organism:
Wenzhouxiangella marina
NCBI taxonomy Id: 1579979
Other names: CGMCC 1.14936, Chromatiales bacterium Ma-11, KCTC 42284, MCCC 1K00261, W. marina, Wenzhouxiangella marina Wang et al. 2015, strain Ma-11
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.