node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AKS42052.1 | AKS42371.1 | WM2015_1682 | WM2015_2005 | ATP-dependent RNA helicase RhlE; Pfam:pfam00270 DEAD/DEAH box helicase; Belongs to the DEAD box helicase family. | Putative Nudix hydrolase NudL; Pfam:pfam00293 NUDIX domain. | 0.581 |
AKS42052.1 | nnrD | WM2015_1682 | WM2015_1850 | ATP-dependent RNA helicase RhlE; Pfam:pfam00270 DEAD/DEAH box helicase; Belongs to the DEAD box helicase family. | YjeF-like protein, hydroxyethylthiazole kinase-related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate d [...] | 0.798 |
AKS42052.1 | rph | WM2015_1682 | WM2015_253 | ATP-dependent RNA helicase RhlE; Pfam:pfam00270 DEAD/DEAH box helicase; Belongs to the DEAD box helicase family. | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.551 |
AKS42175.1 | AKS42371.1 | WM2015_1808 | WM2015_2005 | Hypothetical protein; Pfam:pfam04922 DIE2/ALG10 family. | Putative Nudix hydrolase NudL; Pfam:pfam00293 NUDIX domain. | 0.486 |
AKS42371.1 | AKS42052.1 | WM2015_2005 | WM2015_1682 | Putative Nudix hydrolase NudL; Pfam:pfam00293 NUDIX domain. | ATP-dependent RNA helicase RhlE; Pfam:pfam00270 DEAD/DEAH box helicase; Belongs to the DEAD box helicase family. | 0.581 |
AKS42371.1 | AKS42175.1 | WM2015_2005 | WM2015_1808 | Putative Nudix hydrolase NudL; Pfam:pfam00293 NUDIX domain. | Hypothetical protein; Pfam:pfam04922 DIE2/ALG10 family. | 0.486 |
AKS42371.1 | AKS42372.1 | WM2015_2005 | WM2015_2006 | Putative Nudix hydrolase NudL; Pfam:pfam00293 NUDIX domain. | prolyl-tRNA synthetase; Pfam:pfam06945 Protein of unknown function (DUF1289). | 0.790 |
AKS42371.1 | AKS42373.1 | WM2015_2005 | WM2015_2007 | Putative Nudix hydrolase NudL; Pfam:pfam00293 NUDIX domain. | Peptidyl-prolyl cis-trans isomerase; Pfam:pfam01346 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase. | 0.773 |
AKS42371.1 | birA | WM2015_2005 | WM2015_2817 | Putative Nudix hydrolase NudL; Pfam:pfam00293 NUDIX domain. | biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.579 |
AKS42371.1 | deaD | WM2015_2005 | WM2015_1247 | Putative Nudix hydrolase NudL; Pfam:pfam00293 NUDIX domain. | ATP-dependent RNA helicase DeaD; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. | 0.581 |
AKS42371.1 | nnrD | WM2015_2005 | WM2015_1850 | Putative Nudix hydrolase NudL; Pfam:pfam00293 NUDIX domain. | YjeF-like protein, hydroxyethylthiazole kinase-related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate d [...] | 0.866 |
AKS42371.1 | rhlB | WM2015_2005 | WM2015_1893 | Putative Nudix hydrolase NudL; Pfam:pfam00293 NUDIX domain. | ATP-dependent RNA helicase RhlB; DEAD-box RNA helicase involved in RNA degradation. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. Belongs to the DEAD box helicase family. RhlB subfamily. | 0.581 |
AKS42371.1 | rnr | WM2015_2005 | WM2015_1659 | Putative Nudix hydrolase NudL; Pfam:pfam00293 NUDIX domain. | Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. | 0.651 |
AKS42371.1 | rph | WM2015_2005 | WM2015_253 | Putative Nudix hydrolase NudL; Pfam:pfam00293 NUDIX domain. | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.552 |
AKS42372.1 | AKS42371.1 | WM2015_2006 | WM2015_2005 | prolyl-tRNA synthetase; Pfam:pfam06945 Protein of unknown function (DUF1289). | Putative Nudix hydrolase NudL; Pfam:pfam00293 NUDIX domain. | 0.790 |
AKS42372.1 | AKS42373.1 | WM2015_2006 | WM2015_2007 | prolyl-tRNA synthetase; Pfam:pfam06945 Protein of unknown function (DUF1289). | Peptidyl-prolyl cis-trans isomerase; Pfam:pfam01346 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase. | 0.776 |
AKS42373.1 | AKS42371.1 | WM2015_2007 | WM2015_2005 | Peptidyl-prolyl cis-trans isomerase; Pfam:pfam01346 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase. | Putative Nudix hydrolase NudL; Pfam:pfam00293 NUDIX domain. | 0.773 |
AKS42373.1 | AKS42372.1 | WM2015_2007 | WM2015_2006 | Peptidyl-prolyl cis-trans isomerase; Pfam:pfam01346 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase. | prolyl-tRNA synthetase; Pfam:pfam06945 Protein of unknown function (DUF1289). | 0.776 |
birA | AKS42371.1 | WM2015_2817 | WM2015_2005 | biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Putative Nudix hydrolase NudL; Pfam:pfam00293 NUDIX domain. | 0.579 |
deaD | AKS42371.1 | WM2015_1247 | WM2015_2005 | ATP-dependent RNA helicase DeaD; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. | Putative Nudix hydrolase NudL; Pfam:pfam00293 NUDIX domain. | 0.581 |