node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
OFT22863.1 | polA | HMPREF3175_07110 | HMPREF3175_04545 | Excinuclease ABC subunit A; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.556 |
OFT22863.1 | ruvA | HMPREF3175_07110 | HMPREF3175_09365 | Excinuclease ABC subunit A; Derived by automated computational analysis using gene prediction method: Protein Homology. | Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.401 |
OFT22863.1 | uvrA | HMPREF3175_07110 | HMPREF3175_03125 | Excinuclease ABC subunit A; Derived by automated computational analysis using gene prediction method: Protein Homology. | Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | 0.886 |
OFT22863.1 | uvrB | HMPREF3175_07110 | HMPREF3175_03205 | Excinuclease ABC subunit A; Derived by automated computational analysis using gene prediction method: Protein Homology. | Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] | 0.994 |
OFT22863.1 | uvrC | HMPREF3175_07110 | HMPREF3175_03115 | Excinuclease ABC subunit A; Derived by automated computational analysis using gene prediction method: Protein Homology. | Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.843 |
OFT23833.1 | OFT23834.1 | HMPREF3175_03105 | HMPREF3175_03110 | 2-phospho-L-lactate transferase; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. | RNase adaptor protein RapZ; Displays ATPase and GTPase activities. | 0.967 |
OFT23833.1 | OFT23836.1 | HMPREF3175_03105 | HMPREF3175_03120 | 2-phospho-L-lactate transferase; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. | Acyl-phosphate glycerol 3-phosphate acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.663 |
OFT23833.1 | uvrC | HMPREF3175_03105 | HMPREF3175_03115 | 2-phospho-L-lactate transferase; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. | Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.823 |
OFT23834.1 | OFT23833.1 | HMPREF3175_03110 | HMPREF3175_03105 | RNase adaptor protein RapZ; Displays ATPase and GTPase activities. | 2-phospho-L-lactate transferase; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. | 0.967 |
OFT23834.1 | OFT23836.1 | HMPREF3175_03110 | HMPREF3175_03120 | RNase adaptor protein RapZ; Displays ATPase and GTPase activities. | Acyl-phosphate glycerol 3-phosphate acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.665 |
OFT23834.1 | uvrC | HMPREF3175_03110 | HMPREF3175_03115 | RNase adaptor protein RapZ; Displays ATPase and GTPase activities. | Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.824 |
OFT23836.1 | OFT23833.1 | HMPREF3175_03120 | HMPREF3175_03105 | Acyl-phosphate glycerol 3-phosphate acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2-phospho-L-lactate transferase; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. | 0.663 |
OFT23836.1 | OFT23834.1 | HMPREF3175_03120 | HMPREF3175_03110 | Acyl-phosphate glycerol 3-phosphate acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | RNase adaptor protein RapZ; Displays ATPase and GTPase activities. | 0.665 |
OFT23836.1 | uvrA | HMPREF3175_03120 | HMPREF3175_03125 | Acyl-phosphate glycerol 3-phosphate acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | 0.471 |
OFT23836.1 | uvrC | HMPREF3175_03120 | HMPREF3175_03115 | Acyl-phosphate glycerol 3-phosphate acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.723 |
OFT24242.1 | lexA | HMPREF3175_01795 | HMPREF3175_03810 | Exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. | Repressor LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.472 |
OFT24242.1 | polA | HMPREF3175_01795 | HMPREF3175_04545 | Exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.958 |
OFT24242.1 | uvrB | HMPREF3175_01795 | HMPREF3175_03205 | Exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. | Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] | 0.458 |
OFT24242.1 | uvrC | HMPREF3175_01795 | HMPREF3175_03115 | Exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. | Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.863 |
lexA | OFT24242.1 | HMPREF3175_03810 | HMPREF3175_01795 | Repressor LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | Exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.472 |