node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
HMPREF3175_05225 | OFT22291.1 | HMPREF3175_05225 | HMPREF3175_09325 | Saccharopine dehydrogenase; Incomplete; partial in the middle of a contig; missing start; Derived by automated computational analysis using gene prediction method: Protein Homology. | histidine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.474 |
HMPREF3175_05225 | dxr | HMPREF3175_05225 | HMPREF3175_03610 | Saccharopine dehydrogenase; Incomplete; partial in the middle of a contig; missing start; Derived by automated computational analysis using gene prediction method: Protein Homology. | 1-deoxy-D-xylulose-5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 0.436 |
HMPREF3175_05225 | dxs | HMPREF3175_05225 | HMPREF3175_02165 | Saccharopine dehydrogenase; Incomplete; partial in the middle of a contig; missing start; Derived by automated computational analysis using gene prediction method: Protein Homology. | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | 0.913 |
HMPREF3175_05225 | ispE | HMPREF3175_05225 | HMPREF3175_00050 | Saccharopine dehydrogenase; Incomplete; partial in the middle of a contig; missing start; Derived by automated computational analysis using gene prediction method: Protein Homology. | 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | 0.527 |
HMPREF3175_05225 | ispF | HMPREF3175_05225 | HMPREF3175_00695 | Saccharopine dehydrogenase; Incomplete; partial in the middle of a contig; missing start; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF). Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4 [...] | 0.937 |
HMPREF3175_05225 | ispG | HMPREF3175_05225 | HMPREF3175_03620 | Saccharopine dehydrogenase; Incomplete; partial in the middle of a contig; missing start; Derived by automated computational analysis using gene prediction method: Protein Homology. | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. | 0.916 |
HMPREF3175_05225 | ispH | HMPREF3175_05225 | HMPREF3175_05325 | Saccharopine dehydrogenase; Incomplete; partial in the middle of a contig; missing start; Derived by automated computational analysis using gene prediction method: Protein Homology. | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.532 |
HMPREF3175_05225 | proS | HMPREF3175_05225 | HMPREF3175_03630 | Saccharopine dehydrogenase; Incomplete; partial in the middle of a contig; missing start; Derived by automated computational analysis using gene prediction method: Protein Homology. | proline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacy [...] | 0.510 |
OFT22291.1 | HMPREF3175_05225 | HMPREF3175_09325 | HMPREF3175_05225 | histidine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Saccharopine dehydrogenase; Incomplete; partial in the middle of a contig; missing start; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.474 |
OFT22291.1 | ispG | HMPREF3175_09325 | HMPREF3175_03620 | histidine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. | 0.666 |
OFT22291.1 | proS | HMPREF3175_09325 | HMPREF3175_03630 | histidine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | proline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacy [...] | 0.416 |
OFT23683.1 | OFT23685.1 | HMPREF3175_03615 | HMPREF3175_03625 | Zinc metalloprotease; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 0.648 |
OFT23683.1 | dxr | HMPREF3175_03615 | HMPREF3175_03610 | Zinc metalloprotease; Derived by automated computational analysis using gene prediction method: Protein Homology. | 1-deoxy-D-xylulose-5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 0.883 |
OFT23683.1 | ispG | HMPREF3175_03615 | HMPREF3175_03620 | Zinc metalloprotease; Derived by automated computational analysis using gene prediction method: Protein Homology. | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. | 0.669 |
OFT23683.1 | proS | HMPREF3175_03615 | HMPREF3175_03630 | Zinc metalloprotease; Derived by automated computational analysis using gene prediction method: Protein Homology. | proline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacy [...] | 0.674 |
OFT23685.1 | OFT23683.1 | HMPREF3175_03625 | HMPREF3175_03615 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Zinc metalloprotease; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.648 |
OFT23685.1 | dxr | HMPREF3175_03625 | HMPREF3175_03610 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 1-deoxy-D-xylulose-5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 0.621 |
OFT23685.1 | ispG | HMPREF3175_03625 | HMPREF3175_03620 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. | 0.839 |
OFT23685.1 | proS | HMPREF3175_03625 | HMPREF3175_03630 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | proline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacy [...] | 0.648 |
dxr | HMPREF3175_05225 | HMPREF3175_03610 | HMPREF3175_05225 | 1-deoxy-D-xylulose-5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | Saccharopine dehydrogenase; Incomplete; partial in the middle of a contig; missing start; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.436 |