node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
OFT22493.1 | OFT22946.1 | HMPREF3175_08335 | HMPREF3175_06735 | Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Permease; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.586 |
OFT22946.1 | OFT22493.1 | HMPREF3175_06735 | HMPREF3175_08335 | Permease; Derived by automated computational analysis using gene prediction method: Protein Homology. | Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.586 |
OFT22946.1 | OFT23085.1 | HMPREF3175_06735 | HMPREF3175_06545 | Permease; Derived by automated computational analysis using gene prediction method: Protein Homology. | Nitrate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.738 |
OFT22946.1 | guaA | HMPREF3175_06735 | HMPREF3175_05370 | Permease; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.616 |
OFT22946.1 | guaB | HMPREF3175_06735 | HMPREF3175_05395 | Permease; Derived by automated computational analysis using gene prediction method: Protein Homology. | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.487 |
OFT22946.1 | purC | HMPREF3175_06735 | HMPREF3175_08610 | Permease; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphoribosylaminoimidazolesuccinocarboxamide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SAICAR synthetase family. | 0.455 |
OFT22946.1 | purD | HMPREF3175_06735 | HMPREF3175_08605 | Permease; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphoribosylamine--glycine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GARS family. | 0.458 |
OFT22946.1 | purE | HMPREF3175_06735 | HMPREF3175_00135 | Permease; Derived by automated computational analysis using gene prediction method: Protein Homology. | 5-(carboxyamino)imidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.430 |
OFT22946.1 | purK | HMPREF3175_06735 | HMPREF3175_00130 | Permease; Derived by automated computational analysis using gene prediction method: Protein Homology. | 5-(carboxyamino)imidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.414 |
OFT22946.1 | purL | HMPREF3175_06735 | HMPREF3175_07295 | Permease; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] | 0.434 |
OFT22946.1 | purM | HMPREF3175_06735 | HMPREF3175_08580 | Permease; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphoribosylformylglycinamidine cyclo-ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.410 |
OFT23085.1 | OFT22946.1 | HMPREF3175_06545 | HMPREF3175_06735 | Nitrate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Permease; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.738 |
OFT23085.1 | guaA | HMPREF3175_06545 | HMPREF3175_05370 | Nitrate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.659 |
OFT23085.1 | guaB | HMPREF3175_06545 | HMPREF3175_05395 | Nitrate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.474 |
OFT23085.1 | purE | HMPREF3175_06545 | HMPREF3175_00135 | Nitrate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 5-(carboxyamino)imidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.484 |
guaA | OFT22946.1 | HMPREF3175_05370 | HMPREF3175_06735 | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | Permease; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.616 |
guaA | OFT23085.1 | HMPREF3175_05370 | HMPREF3175_06545 | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | Nitrate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.659 |
guaA | guaB | HMPREF3175_05370 | HMPREF3175_05395 | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.999 |
guaA | purC | HMPREF3175_05370 | HMPREF3175_08610 | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | Phosphoribosylaminoimidazolesuccinocarboxamide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SAICAR synthetase family. | 0.764 |
guaA | purD | HMPREF3175_05370 | HMPREF3175_08605 | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | Phosphoribosylamine--glycine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GARS family. | 0.888 |