STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADY12485.1PFAM: Phosphoribosyltransferase; KEGG: ssm:Spirs_0876 phosphoribosyltransferase. (185 aa)    
Predicted Functional Partners:
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
     
 0.815
ADY12486.1
TIGRFAM: Hypoxanthine phosphoribosyl transferase; KEGG: toc:Toce_2097 hypoxanthine phosphoribosyltransferase; PFAM: Phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
       0.768
hisB
PFAM: Imidazoleglycerol-phosphate dehydratase; TIGRFAM: Histidinol-phosphatase; Histidinol-phosphate phosphatase; HAD-superfamily hydrolase, subfamily IIIA; HAMAP: Imidazoleglycerol-phosphate dehydratase; KEGG: chu:CHU_1270 imidazole glycerol-phosphate dehydratase/histidinol phosphatase; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
      0.681
ADY12483.1
Hypothetical protein.
       0.584
ADY13722.1
TIGRFAM: Thioredoxin reductase; KEGG: sta:STHERM_c07590 thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
  
     0.579
rplF
Ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
  
    0.511
ADY12487.1
KEGG: ere:EUBREC_1253 hypothetical protein.
       0.502
ADY13003.1
PFAM: DNA helicase, UvrD/REP type; KEGG: ssm:Spirs_2383 UvrD/REP helicase.
  
     0.490
ADY13510.1
KEGG: ssm:Spirs_2755 nucleoside diphosphate kinase; PFAM: Nucleoside diphosphate kinase; SMART: Nucleoside diphosphate kinase.
 
   
 0.473
hisC
PFAM: Aminotransferase, class I/classII; TIGRFAM: Histidinol-phosphate aminotransferase; HAMAP: Histidinol-phosphate aminotransferase; KEGG: cpi:Cpin_1819 histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
 
    0.472
Your Current Organism:
Sphaerochaeta globosa
NCBI taxonomy Id: 158189
Other names: S. globosa str. Buddy, Sphaerochaeta globosa str. Buddy, Sphaerochaeta sp. Buddy, Spirochaeta sp. Buddy
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