STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADY12487.1KEGG: ere:EUBREC_1253 hypothetical protein. (171 aa)    
Predicted Functional Partners:
ADY12488.1
Pyruvate dehydrogenase (acetyl-transferring); PFAM: Dehydrogenase, E1 component; Transketolase-like, pyrimidine-binding domain; Transketolase, C-terminal; KEGG: fri:FraEuI1c_5335 dehydrogenase E1 component; SMART: Transketolase-like, pyrimidine-binding domain.
  
    0.587
ADY12485.1
PFAM: Phosphoribosyltransferase; KEGG: ssm:Spirs_0876 phosphoribosyltransferase.
       0.502
ADY12486.1
TIGRFAM: Hypoxanthine phosphoribosyl transferase; KEGG: toc:Toce_2097 hypoxanthine phosphoribosyltransferase; PFAM: Phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
       0.502
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
       0.499
pheS
TIGRFAM: Phenylalanyl-tRNA synthetase, class IIc, alpha subunit; HAMAP: Phenylalanyl-tRNA synthetase alpha chain 2, bacterial/archaeal; KEGG: ssm:Spirs_4136 phenylalanyl-tRNA synthetase, alpha subunit; PFAM: Phenylalanyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.
       0.424
ADY12490.1
SMART: tRNA synthetase, B5; B3/B4 tRNA-binding domain; TIGRFAM: Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archae/euk cytosolic; KEGG: sta:STHERM_c21760 phenylalanyl-tRNA synthetase subunit beta; PFAM: tRNA synthetase, B5.
       0.423
Your Current Organism:
Sphaerochaeta globosa
NCBI taxonomy Id: 158189
Other names: S. globosa str. Buddy, Sphaerochaeta globosa str. Buddy, Sphaerochaeta sp. Buddy, Spirochaeta sp. Buddy
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