STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADY12712.1Adenosylcobinamide-phosphate guanylyltransferase; KEGG: cte:CT0945 cobalamin biosynthesis protein CobP; PFAM: Cobinamide kinase/cobinamide phosphate guanyltransferase. (215 aa)    
Predicted Functional Partners:
cobS
Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
 
 
 0.996
ADY12710.1
Nicotinate-nucleotide/dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
  
 0.995
ADY13782.1
ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; PFAM: Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR; KEGG: rrs:RoseRS_0557 cob(I)alamin adenosyltransferase.
 
  
 0.982
ADY12711.1
PFAM: Xylose isomerase, TIM barrel domain; KEGG: dal:Dalk_0459 xylose isomerase domain protein TIM barrel.
 
     0.784
ADY12714.1
KEGG: sta:STHERM_c21790 hypothetical protein; TIGRFAM: Phosphoserine phosphatase/homoserine phosphotransferase bifunctional protein; PFAM: Haloacid dehalogenase-like hydrolase.
       0.618
ADY12715.1
Hypothetical protein.
       0.618
ADY12716.1
PFAM: Protein of unknown function DUF62; KEGG: ssm:Spirs_3587 protein of unknown function DUF62.
       0.618
ADY12717.1
PFAM: Protein of unknown function DUF1393; KEGG: ssm:Spirs_3589 protein of unknown function DUF1393.
       0.546
ADY12709.1
PFAM: Protein of unknown function DUF606; KEGG: cpy:Cphy_1299 hypothetical protein.
       0.532
ADY11880.1
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
 
   
 0.529
Your Current Organism:
Sphaerochaeta globosa
NCBI taxonomy Id: 158189
Other names: S. globosa str. Buddy, Sphaerochaeta globosa str. Buddy, Sphaerochaeta sp. Buddy, Spirochaeta sp. Buddy
Server load: low (22%) [HD]