STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aptAdenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (177 aa)    
Predicted Functional Partners:
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
  
 0.994
ADY12469.1
KEGG: purB; adenylosuccinate lyase; TIGRFAM: Adenylosuccinate lyase; PFAM: Adenylosuccinate lyase C-terminal metazoa/fungi; Lyase 1, N-terminal; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
  
 0.960
ADY13970.1
Phosphoribosylaminoimidazolecarboxamide formyltransferase; PFAM: AICARFT/IMPCHase bienzyme, transformylase domain; KEGG: bvu:BVU_1693 5-aminoimidazole-4-carboxamide ribonucleotide transformylase; SMART: AICARFT/IMPCHase bienzyme, transformylase domain.
  
 0.955
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
  
 
 0.938
ADY12486.1
TIGRFAM: Hypoxanthine phosphoribosyl transferase; KEGG: toc:Toce_2097 hypoxanthine phosphoribosyltransferase; PFAM: Phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
   
 0.931
ADY14803.1
Inosine guanosine and xanthosine phosphorylase family; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
  
 
 0.928
ADY13751.1
5'-nucleotidase; KEGG: ppm:PPSC2_c1154 5-nucleotidase domain protein; PFAM: 5'-Nucleotidase, C-terminal; Metallo-dependent phosphatase.
  
 
 0.923
ADY12759.1
KEGG: tai:Taci_0564 ribosylpyrimidine nucleosidase; PFAM: Inosine/uridine-preferring nucleoside hydrolase domain.
    
 0.917
ade
Adenine deaminase; PFAM: Amidohydrolase 1; TIGRFAM: Adenine deaminase; HAMAP: Adenine deaminase; KEGG: ssm:Spirs_2944 adenine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.
    
 0.917
ade-2
Adenine deaminase; PFAM: Amidohydrolase 1; TIGRFAM: Adenine deaminase; HAMAP: Adenine deaminase; KEGG: dps:DP1374 adenine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.
    
 0.917
Your Current Organism:
Sphaerochaeta globosa
NCBI taxonomy Id: 158189
Other names: S. globosa str. Buddy, Sphaerochaeta globosa str. Buddy, Sphaerochaeta sp. Buddy, Spirochaeta sp. Buddy
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.