STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADY13427.1KEGG: ssm:Spirs_2695 two component transcriptional regulator, winged helix family; PFAM: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal. (230 aa)    
Predicted Functional Partners:
ADY13426.1
KEGG: ssm:Spirs_2696 histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; HAMP linker domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain.
 
 0.968
ADY14363.1
Hpt sensor hybrid histidine kinase; KEGG: cst:CLOST_1047 histidine kinase; PFAM: ATPase-like, ATP-binding domain; Extracellular solute-binding protein, family 3; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Signal transduction response regulator, receiver domain; Signal transduction histidine kinase, phosphotransfer (Hpt) domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Extracellular solute-binding protein, family 3; Signal transduction response regulator, rec [...]
 
 
 0.941
ADY14392.1
TIGRFAM: PAS; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS fold; GCN5-related N-acetyltransferase (GNAT) domain; KEGG: dsa:Desal_0288 PAS/PAC sensor signal transduction histidine kinase; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS.
 
 
 0.929
ADY13502.1
KEGG: ssm:Spirs_1696 multi-sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; HAMP linker domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; HAMP linker domain; PAS.
 
 0.879
ADY12041.1
KEGG: ssm:Spirs_3954 integral membrane sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain.
 
 
 0.843
ADY12005.1
Diguanylate cyclase and metal dependent phosphohydrolase; TIGRFAM: Diguanylate cyclase, predicted; PAS; Uncharacterised protein family HDIG; PFAM: Diguanylate cyclase, predicted; PAS fold-3; CHASE3; PAS fold; Metal-dependent phosphohydrolase, HD subdomain; KEGG: csh:Closa_3879 diguanylate cyclase and metal dependent phosphohydrolase; SMART: Diguanylate cyclase, predicted; PAC motif; PAS; Metal-dependent phosphohydrolase, HD domain.
  
 
 0.790
ADY12633.1
KEGG: ssm:Spirs_0495 integral membrane sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain.
 
 
 0.790
ADY14342.1
Diguanylate cyclase and metal dependent phosphohydrolase; TIGRFAM: Diguanylate cyclase, predicted; PAS; Uncharacterised protein family HDIG; PFAM: Diguanylate cyclase, predicted; HAMP linker domain; PAS fold; Metal-dependent phosphohydrolase, HD subdomain; KEGG: csh:Closa_2542 diguanylate cyclase and metal dependent phosphohydrolase; SMART: Diguanylate cyclase, predicted; HAMP linker domain; PAS; Metal-dependent phosphohydrolase, HD domain.
  
 
 0.790
ADY13106.1
KEGG: ssm:Spirs_1708 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS fold; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain.
  
 
 
 0.732
ADY13344.1
Putative PAS/PAC sensor protein; TIGRFAM: PAS; PFAM: PAS fold; PAS fold-4; KEGG: signal transduction histidine kinase, nitrogen specific, NtrB; SMART: PAS; PAC motif.
 
 
 0.639
Your Current Organism:
Sphaerochaeta globosa
NCBI taxonomy Id: 158189
Other names: S. globosa str. Buddy, Sphaerochaeta globosa str. Buddy, Sphaerochaeta sp. Buddy, Spirochaeta sp. Buddy
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.