STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADY13457.1KEGG: ssm:Spirs_2352 metal dependent phosphohydrolase; PFAM: Metal-dependent phosphohydrolase, HD subdomain; SMART: Metal-dependent phosphohydrolase, HD domain. (419 aa)    
Predicted Functional Partners:
ADY13458.1
PP-loop domain protein; PFAM: tRNA(Ile)-lysidine/2-thiocytidine synthase; KEGG: ssm:Spirs_2353 PP-loop domain protein; Belongs to the TtcA family.
       0.786
cmk-2
KEGG: ssm:Spirs_2280 cytidylate kinase; TIGRFAM: Cytidylate kinase, putative; PFAM: Cytidylate kinase domain.
  
     0.610
ADY13888.1
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
 
     0.593
ADY13459.1
KEGG: ssm:Spirs_2359 hypothetical protein.
       0.565
ADY13456.1
Type III effector Hrp-dependent outer; PFAM: Protein of unknown function, DUF1537; KEGG: lcz:LCAZH_2706 hypothetical protein.
       0.541
ADY13455.1
4-hydroxythreonine-4-phosphate dehydrogenase; PFAM: Pyridoxal phosphate (active vitamin B6) biosynthesis PdxA; TIGRFAM: Pyridoxal phosphate (active vitamin B6) biosynthesis PdxA; HAMAP: Pyridoxal phosphate (active vitamin B6) biosynthesis PdxA; KEGG: ipo:Ilyop_0077 4-hydroxythreonine-4-phosphate dehydrogenase; Belongs to the PdxA family.
       0.537
ADY13460.1
Hypothetical protein; KEGG: dya:Dyak_GE24546 GE24546 gene product from transcript GE24546-RA.
       0.522
ADY13601.1
PFAM: Domain of unknown function DUF814; Fibronectin-binding A, N-terminal; KEGG: ssm:Spirs_2274 fibronectin-binding A domain protein.
  
     0.473
mutL
DNA mismatch repair protein mutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
     
 0.445
rnz
Ribonuclease Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family.
  
     0.436
Your Current Organism:
Sphaerochaeta globosa
NCBI taxonomy Id: 158189
Other names: S. globosa str. Buddy, Sphaerochaeta globosa str. Buddy, Sphaerochaeta sp. Buddy, Spirochaeta sp. Buddy
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