node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADY13598.1 | ADY13797.1 | SpiBuddy_1774 | SpiBuddy_1974 | Protein of unknown function UPF0044; PFAM: RNA-binding, CRM domain; KEGG: mgm:Mmc1_3700 hypothetical protein. | Metal dependent phosphohydrolase; TIGRFAM: Conserved hypothetical protein CHP00488; Uncharacterised protein family HDIG; PFAM: Metal-dependent phosphohydrolase, HD subdomain; KEGG: ssm:Spirs_1807 metal dependent phosphohydrolase; SMART: Metal-dependent phosphohydrolase, HD domain. | 0.516 |
ADY13598.1 | aroE | SpiBuddy_1774 | SpiBuddy_0226 | Protein of unknown function UPF0044; PFAM: RNA-binding, CRM domain; KEGG: mgm:Mmc1_3700 hypothetical protein. | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.451 |
ADY13598.1 | aroE-2 | SpiBuddy_1774 | SpiBuddy_1224 | Protein of unknown function UPF0044; PFAM: RNA-binding, CRM domain; KEGG: mgm:Mmc1_3700 hypothetical protein. | 3-dehydroquinate dehydratase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.458 |
ADY13598.1 | nadD | SpiBuddy_1774 | SpiBuddy_1975 | Protein of unknown function UPF0044; PFAM: RNA-binding, CRM domain; KEGG: mgm:Mmc1_3700 hypothetical protein. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.756 |
ADY13598.1 | rsfS | SpiBuddy_1774 | SpiBuddy_1972 | Protein of unknown function UPF0044; PFAM: RNA-binding, CRM domain; KEGG: mgm:Mmc1_3700 hypothetical protein. | Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.535 |
ADY13796.1 | ADY13797.1 | SpiBuddy_1973 | SpiBuddy_1974 | Hypothetical protein. | Metal dependent phosphohydrolase; TIGRFAM: Conserved hypothetical protein CHP00488; Uncharacterised protein family HDIG; PFAM: Metal-dependent phosphohydrolase, HD subdomain; KEGG: ssm:Spirs_1807 metal dependent phosphohydrolase; SMART: Metal-dependent phosphohydrolase, HD domain. | 0.773 |
ADY13796.1 | ADY13802.1 | SpiBuddy_1973 | SpiBuddy_1979 | Hypothetical protein. | Regulatory protein TetR; PFAM: Transcription regulator, TetR-like, DNA-binding, bacterial/archaeal; KEGG: btk:BT9727_0971 TetR family transcriptional regulator. | 0.471 |
ADY13796.1 | nadD | SpiBuddy_1973 | SpiBuddy_1975 | Hypothetical protein. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.773 |
ADY13796.1 | obg | SpiBuddy_1973 | SpiBuddy_1976 | Hypothetical protein. | GTPase obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.768 |
ADY13796.1 | rplU | SpiBuddy_1973 | SpiBuddy_1978 | Hypothetical protein. | 50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.656 |
ADY13796.1 | rpmA | SpiBuddy_1973 | SpiBuddy_1977 | Hypothetical protein. | TIGRFAM: Ribosomal protein L27; HAMAP: Ribosomal protein L27; KEGG: sta:STHERM_c10280 50S ribosomal protein L27; PFAM: Ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family. | 0.670 |
ADY13796.1 | rsfS | SpiBuddy_1973 | SpiBuddy_1972 | Hypothetical protein. | Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.773 |
ADY13797.1 | ADY13598.1 | SpiBuddy_1974 | SpiBuddy_1774 | Metal dependent phosphohydrolase; TIGRFAM: Conserved hypothetical protein CHP00488; Uncharacterised protein family HDIG; PFAM: Metal-dependent phosphohydrolase, HD subdomain; KEGG: ssm:Spirs_1807 metal dependent phosphohydrolase; SMART: Metal-dependent phosphohydrolase, HD domain. | Protein of unknown function UPF0044; PFAM: RNA-binding, CRM domain; KEGG: mgm:Mmc1_3700 hypothetical protein. | 0.516 |
ADY13797.1 | ADY13796.1 | SpiBuddy_1974 | SpiBuddy_1973 | Metal dependent phosphohydrolase; TIGRFAM: Conserved hypothetical protein CHP00488; Uncharacterised protein family HDIG; PFAM: Metal-dependent phosphohydrolase, HD subdomain; KEGG: ssm:Spirs_1807 metal dependent phosphohydrolase; SMART: Metal-dependent phosphohydrolase, HD domain. | Hypothetical protein. | 0.773 |
ADY13797.1 | ADY13802.1 | SpiBuddy_1974 | SpiBuddy_1979 | Metal dependent phosphohydrolase; TIGRFAM: Conserved hypothetical protein CHP00488; Uncharacterised protein family HDIG; PFAM: Metal-dependent phosphohydrolase, HD subdomain; KEGG: ssm:Spirs_1807 metal dependent phosphohydrolase; SMART: Metal-dependent phosphohydrolase, HD domain. | Regulatory protein TetR; PFAM: Transcription regulator, TetR-like, DNA-binding, bacterial/archaeal; KEGG: btk:BT9727_0971 TetR family transcriptional regulator. | 0.471 |
ADY13797.1 | aroE | SpiBuddy_1974 | SpiBuddy_0226 | Metal dependent phosphohydrolase; TIGRFAM: Conserved hypothetical protein CHP00488; Uncharacterised protein family HDIG; PFAM: Metal-dependent phosphohydrolase, HD subdomain; KEGG: ssm:Spirs_1807 metal dependent phosphohydrolase; SMART: Metal-dependent phosphohydrolase, HD domain. | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.512 |
ADY13797.1 | aroE-2 | SpiBuddy_1974 | SpiBuddy_1224 | Metal dependent phosphohydrolase; TIGRFAM: Conserved hypothetical protein CHP00488; Uncharacterised protein family HDIG; PFAM: Metal-dependent phosphohydrolase, HD subdomain; KEGG: ssm:Spirs_1807 metal dependent phosphohydrolase; SMART: Metal-dependent phosphohydrolase, HD domain. | 3-dehydroquinate dehydratase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.513 |
ADY13797.1 | nadD | SpiBuddy_1974 | SpiBuddy_1975 | Metal dependent phosphohydrolase; TIGRFAM: Conserved hypothetical protein CHP00488; Uncharacterised protein family HDIG; PFAM: Metal-dependent phosphohydrolase, HD subdomain; KEGG: ssm:Spirs_1807 metal dependent phosphohydrolase; SMART: Metal-dependent phosphohydrolase, HD domain. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.965 |
ADY13797.1 | obg | SpiBuddy_1974 | SpiBuddy_1976 | Metal dependent phosphohydrolase; TIGRFAM: Conserved hypothetical protein CHP00488; Uncharacterised protein family HDIG; PFAM: Metal-dependent phosphohydrolase, HD subdomain; KEGG: ssm:Spirs_1807 metal dependent phosphohydrolase; SMART: Metal-dependent phosphohydrolase, HD domain. | GTPase obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.808 |
ADY13797.1 | rplU | SpiBuddy_1974 | SpiBuddy_1978 | Metal dependent phosphohydrolase; TIGRFAM: Conserved hypothetical protein CHP00488; Uncharacterised protein family HDIG; PFAM: Metal-dependent phosphohydrolase, HD subdomain; KEGG: ssm:Spirs_1807 metal dependent phosphohydrolase; SMART: Metal-dependent phosphohydrolase, HD domain. | 50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.699 |