node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADY12155.1 | ADY13901.1 | SpiBuddy_0319 | SpiBuddy_2080 | Transcriptional regulator, GntR family with UTRA sensor domain; KEGG: tle:Tlet_0191 GntR family transcriptional regulator; PFAM: UbiC transcription regulator-associated; HTH transcriptional regulator, GntR; SMART: UbiC transcription regulator-associated; HTH transcriptional regulator, GntR. | Helix-turn-helix domain protein; KEGG: ssm:Spirs_2303 transcriptional regulator, XRE family; PFAM: Helix-turn-helix type 3; Cupin 2, conserved barrel; SMART: Helix-turn-helix type 3. | 0.517 |
ADY12337.1 | ADY13901.1 | SpiBuddy_0504 | SpiBuddy_2080 | Transcriptional regulator, AraC family; KEGG: rba:RB680 L-rhamnose operon transcriptional activator; PFAM: HTH transcriptional regulator, AraC, arabinose-binding/dimerisation; HTH transcriptional regulator, AraC; SMART: Helix-turn-helix, AraC type, DNA binding domain. | Helix-turn-helix domain protein; KEGG: ssm:Spirs_2303 transcriptional regulator, XRE family; PFAM: Helix-turn-helix type 3; Cupin 2, conserved barrel; SMART: Helix-turn-helix type 3. | 0.596 |
ADY12693.1 | ADY13901.1 | SpiBuddy_0866 | SpiBuddy_2080 | KEGG: dal:Dalk_3958 transcriptional regulator, GntR family; PFAM: HTH transcriptional regulator, GntR; UbiC transcription regulator-associated; SMART: HTH transcriptional regulator, GntR; UbiC transcription regulator-associated. | Helix-turn-helix domain protein; KEGG: ssm:Spirs_2303 transcriptional regulator, XRE family; PFAM: Helix-turn-helix type 3; Cupin 2, conserved barrel; SMART: Helix-turn-helix type 3. | 0.575 |
ADY12693.1 | ADY14796.1 | SpiBuddy_0866 | SpiBuddy_2990 | KEGG: dal:Dalk_3958 transcriptional regulator, GntR family; PFAM: HTH transcriptional regulator, GntR; UbiC transcription regulator-associated; SMART: HTH transcriptional regulator, GntR; UbiC transcription regulator-associated. | KEGG: ssm:Spirs_1347 GntR domain protein; PFAM: HTH transcriptional regulator, GntR; SMART: HTH transcriptional regulator, GntR. | 0.430 |
ADY13192.1 | ADY13901.1 | SpiBuddy_1367 | SpiBuddy_2080 | TrkA-C domain protein; KEGG: cpf:CPF_2589 GntR family transcriptional regulator; PFAM: Regulator of K+ conductance, C-terminal; HTH transcriptional regulator, GntR; SMART: HTH transcriptional regulator, GntR. | Helix-turn-helix domain protein; KEGG: ssm:Spirs_2303 transcriptional regulator, XRE family; PFAM: Helix-turn-helix type 3; Cupin 2, conserved barrel; SMART: Helix-turn-helix type 3. | 0.519 |
ADY13900.1 | ADY13901.1 | SpiBuddy_2079 | SpiBuddy_2080 | L-threonine 3-dehydrogenase; KEGG: bcy:Bcer98_0534 NAD-dependent epimerase/dehydratase; PFAM: NAD-dependent epimerase/dehydratase. | Helix-turn-helix domain protein; KEGG: ssm:Spirs_2303 transcriptional regulator, XRE family; PFAM: Helix-turn-helix type 3; Cupin 2, conserved barrel; SMART: Helix-turn-helix type 3. | 0.564 |
ADY13900.1 | ADY13902.1 | SpiBuddy_2079 | SpiBuddy_2081 | L-threonine 3-dehydrogenase; KEGG: bcy:Bcer98_0534 NAD-dependent epimerase/dehydratase; PFAM: NAD-dependent epimerase/dehydratase. | PFAM: Major facilitator superfamily MFS-1; KEGG: pjd:Pjdr2_6129 major facilitator superfamily MFS_1. | 0.414 |
ADY13900.1 | kbl | SpiBuddy_2079 | SpiBuddy_2078 | L-threonine 3-dehydrogenase; KEGG: bcy:Bcer98_0534 NAD-dependent epimerase/dehydratase; PFAM: NAD-dependent epimerase/dehydratase. | 2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. | 0.934 |
ADY13901.1 | ADY12155.1 | SpiBuddy_2080 | SpiBuddy_0319 | Helix-turn-helix domain protein; KEGG: ssm:Spirs_2303 transcriptional regulator, XRE family; PFAM: Helix-turn-helix type 3; Cupin 2, conserved barrel; SMART: Helix-turn-helix type 3. | Transcriptional regulator, GntR family with UTRA sensor domain; KEGG: tle:Tlet_0191 GntR family transcriptional regulator; PFAM: UbiC transcription regulator-associated; HTH transcriptional regulator, GntR; SMART: UbiC transcription regulator-associated; HTH transcriptional regulator, GntR. | 0.517 |
ADY13901.1 | ADY12337.1 | SpiBuddy_2080 | SpiBuddy_0504 | Helix-turn-helix domain protein; KEGG: ssm:Spirs_2303 transcriptional regulator, XRE family; PFAM: Helix-turn-helix type 3; Cupin 2, conserved barrel; SMART: Helix-turn-helix type 3. | Transcriptional regulator, AraC family; KEGG: rba:RB680 L-rhamnose operon transcriptional activator; PFAM: HTH transcriptional regulator, AraC, arabinose-binding/dimerisation; HTH transcriptional regulator, AraC; SMART: Helix-turn-helix, AraC type, DNA binding domain. | 0.596 |
ADY13901.1 | ADY12693.1 | SpiBuddy_2080 | SpiBuddy_0866 | Helix-turn-helix domain protein; KEGG: ssm:Spirs_2303 transcriptional regulator, XRE family; PFAM: Helix-turn-helix type 3; Cupin 2, conserved barrel; SMART: Helix-turn-helix type 3. | KEGG: dal:Dalk_3958 transcriptional regulator, GntR family; PFAM: HTH transcriptional regulator, GntR; UbiC transcription regulator-associated; SMART: HTH transcriptional regulator, GntR; UbiC transcription regulator-associated. | 0.575 |
ADY13901.1 | ADY13192.1 | SpiBuddy_2080 | SpiBuddy_1367 | Helix-turn-helix domain protein; KEGG: ssm:Spirs_2303 transcriptional regulator, XRE family; PFAM: Helix-turn-helix type 3; Cupin 2, conserved barrel; SMART: Helix-turn-helix type 3. | TrkA-C domain protein; KEGG: cpf:CPF_2589 GntR family transcriptional regulator; PFAM: Regulator of K+ conductance, C-terminal; HTH transcriptional regulator, GntR; SMART: HTH transcriptional regulator, GntR. | 0.519 |
ADY13901.1 | ADY13900.1 | SpiBuddy_2080 | SpiBuddy_2079 | Helix-turn-helix domain protein; KEGG: ssm:Spirs_2303 transcriptional regulator, XRE family; PFAM: Helix-turn-helix type 3; Cupin 2, conserved barrel; SMART: Helix-turn-helix type 3. | L-threonine 3-dehydrogenase; KEGG: bcy:Bcer98_0534 NAD-dependent epimerase/dehydratase; PFAM: NAD-dependent epimerase/dehydratase. | 0.564 |
ADY13901.1 | ADY13902.1 | SpiBuddy_2080 | SpiBuddy_2081 | Helix-turn-helix domain protein; KEGG: ssm:Spirs_2303 transcriptional regulator, XRE family; PFAM: Helix-turn-helix type 3; Cupin 2, conserved barrel; SMART: Helix-turn-helix type 3. | PFAM: Major facilitator superfamily MFS-1; KEGG: pjd:Pjdr2_6129 major facilitator superfamily MFS_1. | 0.583 |
ADY13901.1 | ADY13905.1 | SpiBuddy_2080 | SpiBuddy_2084 | Helix-turn-helix domain protein; KEGG: ssm:Spirs_2303 transcriptional regulator, XRE family; PFAM: Helix-turn-helix type 3; Cupin 2, conserved barrel; SMART: Helix-turn-helix type 3. | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.497 |
ADY13901.1 | ADY14796.1 | SpiBuddy_2080 | SpiBuddy_2990 | Helix-turn-helix domain protein; KEGG: ssm:Spirs_2303 transcriptional regulator, XRE family; PFAM: Helix-turn-helix type 3; Cupin 2, conserved barrel; SMART: Helix-turn-helix type 3. | KEGG: ssm:Spirs_1347 GntR domain protein; PFAM: HTH transcriptional regulator, GntR; SMART: HTH transcriptional regulator, GntR. | 0.505 |
ADY13901.1 | kbl | SpiBuddy_2080 | SpiBuddy_2078 | Helix-turn-helix domain protein; KEGG: ssm:Spirs_2303 transcriptional regulator, XRE family; PFAM: Helix-turn-helix type 3; Cupin 2, conserved barrel; SMART: Helix-turn-helix type 3. | 2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. | 0.662 |
ADY13901.1 | prmC | SpiBuddy_2080 | SpiBuddy_2083 | Helix-turn-helix domain protein; KEGG: ssm:Spirs_2303 transcriptional regulator, XRE family; PFAM: Helix-turn-helix type 3; Cupin 2, conserved barrel; SMART: Helix-turn-helix type 3. | protein-(glutamine-N5) methyltransferase, release factor-specific; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily. | 0.463 |
ADY13902.1 | ADY13900.1 | SpiBuddy_2081 | SpiBuddy_2079 | PFAM: Major facilitator superfamily MFS-1; KEGG: pjd:Pjdr2_6129 major facilitator superfamily MFS_1. | L-threonine 3-dehydrogenase; KEGG: bcy:Bcer98_0534 NAD-dependent epimerase/dehydratase; PFAM: NAD-dependent epimerase/dehydratase. | 0.414 |
ADY13902.1 | ADY13901.1 | SpiBuddy_2081 | SpiBuddy_2080 | PFAM: Major facilitator superfamily MFS-1; KEGG: pjd:Pjdr2_6129 major facilitator superfamily MFS_1. | Helix-turn-helix domain protein; KEGG: ssm:Spirs_2303 transcriptional regulator, XRE family; PFAM: Helix-turn-helix type 3; Cupin 2, conserved barrel; SMART: Helix-turn-helix type 3. | 0.583 |