STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADY14001.1KEGG: gdj:Gdia_3096 short-chain dehydrogenase/reductase SDR; PFAM: Short-chain dehydrogenase/reductase SDR. (260 aa)    
Predicted Functional Partners:
ADY13882.1
KEGG: ssm:Spirs_0598 oxidoreductase FAD/NAD(P)-binding domain protein; PFAM: Oxidoreductase FAD/NAD(P)-binding; Oxidoreductase, FAD-binding domain; Ferredoxin.
 
      0.872
ADY11985.1
PFAM: Short-chain dehydrogenase/reductase SDR; KEGG: rlt:Rleg2_0558 short chain dehydrogenase.
 
 
 0.725
ADY12304.1
(Acyl-carrier-protein) S-malonyltransferase; KEGG: sta:STHERM_c21550 hypothetical protein; SMART: Polyketide synthase, acyl transferase domain.
 
 0.653
ADY12302.1
3-oxoacyl-(acyl-carrier-protein) synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 
 0.601
ADY12389.1
PfkB domain protein; PFAM: Carbohydrate/purine kinase; KEGG: ssm:Spirs_0877 PfkB domain protein.
  
  
 0.542
ADY14002.1
PFAM: Drug/metabolite transporter; KEGG: str:Sterm_1343 protein of unknown function DUF6 transmembrane.
     
 0.537
ADY12301.1
PFAM: Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase, FabA/FabZ; KEGG: sta:STHERM_c08550 beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ.
 
 
 0.519
cas1
CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
  
    0.510
ADY14363.1
Hpt sensor hybrid histidine kinase; KEGG: cst:CLOST_1047 histidine kinase; PFAM: ATPase-like, ATP-binding domain; Extracellular solute-binding protein, family 3; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Signal transduction response regulator, receiver domain; Signal transduction histidine kinase, phosphotransfer (Hpt) domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Extracellular solute-binding protein, family 3; Signal transduction response regulator, rec [...]
  
 
 0.508
ADY14858.1
Peptidylprolyl isomerase; KEGG: dps:DP1645 peptidyl-prolyl cis-trans isomerase; PFAM: Peptidyl-prolyl cis-trans isomerase, cyclophilin-type; Peptidyl-prolyl cis-trans isomerase, FKBP-type.
   
 
 0.501
Your Current Organism:
Sphaerochaeta globosa
NCBI taxonomy Id: 158189
Other names: S. globosa str. Buddy, Sphaerochaeta globosa str. Buddy, Sphaerochaeta sp. Buddy, Spirochaeta sp. Buddy
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