node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AEV28252.1 | AEV28253.1 | SpiGrapes_0394 | SpiGrapes_0395 | Hypothetical protein; PFAM: Formylglycine-generating sulfatase enzyme. | PFAM: Peptidase S26; TIGRFAM: signal peptidase I, bacterial type; Belongs to the peptidase S26 family. | 0.693 |
AEV28252.1 | AEV28254.1 | SpiGrapes_0394 | SpiGrapes_0396 | Hypothetical protein; PFAM: Formylglycine-generating sulfatase enzyme. | Putative oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.577 |
AEV28252.1 | AEV28255.1 | SpiGrapes_0394 | SpiGrapes_0397 | Hypothetical protein; PFAM: Formylglycine-generating sulfatase enzyme. | PFAM: Domain of unknown function DUF28; TIGRFAM: DNA-binding regulatory protein, YebC/PmpR family. | 0.433 |
AEV28252.1 | AEV28579.1 | SpiGrapes_0394 | SpiGrapes_0743 | Hypothetical protein; PFAM: Formylglycine-generating sulfatase enzyme. | PFAM: ATP synthase (C/AC39) subunit. | 0.682 |
AEV28252.1 | queA | SpiGrapes_0394 | SpiGrapes_0401 | Hypothetical protein; PFAM: Formylglycine-generating sulfatase enzyme. | S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | 0.432 |
AEV28252.1 | ruvB | SpiGrapes_0394 | SpiGrapes_0400 | Hypothetical protein; PFAM: Formylglycine-generating sulfatase enzyme. | Holliday junction DNA helicase, RuvB subunit; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.432 |
AEV28252.1 | ruvC | SpiGrapes_0394 | SpiGrapes_0398 | Hypothetical protein; PFAM: Formylglycine-generating sulfatase enzyme. | Holliday junction resolvasome, endonuclease subunit; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.433 |
AEV28252.1 | smpB | SpiGrapes_0394 | SpiGrapes_0393 | Hypothetical protein; PFAM: Formylglycine-generating sulfatase enzyme. | SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...] | 0.802 |
AEV28253.1 | AEV28252.1 | SpiGrapes_0395 | SpiGrapes_0394 | PFAM: Peptidase S26; TIGRFAM: signal peptidase I, bacterial type; Belongs to the peptidase S26 family. | Hypothetical protein; PFAM: Formylglycine-generating sulfatase enzyme. | 0.693 |
AEV28253.1 | AEV28254.1 | SpiGrapes_0395 | SpiGrapes_0396 | PFAM: Peptidase S26; TIGRFAM: signal peptidase I, bacterial type; Belongs to the peptidase S26 family. | Putative oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.795 |
AEV28253.1 | AEV28255.1 | SpiGrapes_0395 | SpiGrapes_0397 | PFAM: Peptidase S26; TIGRFAM: signal peptidase I, bacterial type; Belongs to the peptidase S26 family. | PFAM: Domain of unknown function DUF28; TIGRFAM: DNA-binding regulatory protein, YebC/PmpR family. | 0.633 |
AEV28253.1 | AEV28579.1 | SpiGrapes_0395 | SpiGrapes_0743 | PFAM: Peptidase S26; TIGRFAM: signal peptidase I, bacterial type; Belongs to the peptidase S26 family. | PFAM: ATP synthase (C/AC39) subunit. | 0.745 |
AEV28253.1 | lepA | SpiGrapes_0395 | SpiGrapes_3023 | PFAM: Peptidase S26; TIGRFAM: signal peptidase I, bacterial type; Belongs to the peptidase S26 family. | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.629 |
AEV28253.1 | queA | SpiGrapes_0395 | SpiGrapes_0401 | PFAM: Peptidase S26; TIGRFAM: signal peptidase I, bacterial type; Belongs to the peptidase S26 family. | S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | 0.597 |
AEV28253.1 | rnhB | SpiGrapes_0395 | SpiGrapes_0502 | PFAM: Peptidase S26; TIGRFAM: signal peptidase I, bacterial type; Belongs to the peptidase S26 family. | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.612 |
AEV28253.1 | ruvB | SpiGrapes_0395 | SpiGrapes_0400 | PFAM: Peptidase S26; TIGRFAM: signal peptidase I, bacterial type; Belongs to the peptidase S26 family. | Holliday junction DNA helicase, RuvB subunit; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.620 |
AEV28253.1 | ruvC | SpiGrapes_0395 | SpiGrapes_0398 | PFAM: Peptidase S26; TIGRFAM: signal peptidase I, bacterial type; Belongs to the peptidase S26 family. | Holliday junction resolvasome, endonuclease subunit; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.632 |
AEV28253.1 | smpB | SpiGrapes_0395 | SpiGrapes_0393 | PFAM: Peptidase S26; TIGRFAM: signal peptidase I, bacterial type; Belongs to the peptidase S26 family. | SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...] | 0.597 |
AEV28254.1 | AEV28252.1 | SpiGrapes_0396 | SpiGrapes_0394 | Putative oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Hypothetical protein; PFAM: Formylglycine-generating sulfatase enzyme. | 0.577 |
AEV28254.1 | AEV28253.1 | SpiGrapes_0396 | SpiGrapes_0395 | Putative oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | PFAM: Peptidase S26; TIGRFAM: signal peptidase I, bacterial type; Belongs to the peptidase S26 family. | 0.795 |