STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KLI76081.1Hypothetical protein; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. (342 aa)    
Predicted Functional Partners:
KLI76080.1
ATPase P; Displays ATPase and GTPase activities.
  
  
 0.969
whiA
Sporulation regulator WhiA; Involved in cell division and chromosome segregation.
 
  
 0.969
uvrA
Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
       0.706
uvrB
Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
       0.669
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
   0.640
KLI76652.1
Protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.631
KLI76083.1
MarR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.630
KLI76428.1
Pyruvate kinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.615
KLI75923.1
LytR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.597
KLI76653.1
16S rRNA methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
  
    0.583
Your Current Organism:
Lactobacillus casei
NCBI taxonomy Id: 1582
Other names: ATCC 393, BCRC 10697, Bacillus a, Bacillus casei a, Bacterium casei a, CCRC 10697, CCRC:10697, CECT 475, CIP 103137, Caseobacterium vulgare, DSM 20011, IAM 12473, IFO 15883, KCTC 3109, L. casei, LMG 6904, LMG:6904, Lactobacillus casei subsp. casei, Lactobacillus sp. NCIM 2363, Lactobacillus sp. NCIM 2732, Lactobacillus sp. T2, Lactobacillus sp. T20, Lactobacterium casei, NBRC 15883, NCDO 161, NCIMB 11970, NCTC 13641, Streptobacterium casei, strain Hucker03, strain Orla-Jensen 7, strain OrlandL-323, strain Tittsler303
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