node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KLI76212.1 | KLI76213.1 | AAW28_03300 | AAW28_03305 | Uric acid permease PucJ; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphoribosylaminoimidazole carboxylase; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate. Belongs to the PurK/PurT family. | 0.820 |
KLI76212.1 | KLI76214.1 | AAW28_03300 | AAW28_03310 | Uric acid permease PucJ; Derived by automated computational analysis using gene prediction method: Protein Homology. | Adenylosuccinate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.675 |
KLI76212.1 | carA | AAW28_03300 | AAW28_04845 | Uric acid permease PucJ; Derived by automated computational analysis using gene prediction method: Protein Homology. | Carbamoyl phosphate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarA family. | 0.668 |
KLI76212.1 | guaA | AAW28_03300 | AAW28_01830 | Uric acid permease PucJ; Derived by automated computational analysis using gene prediction method: Protein Homology. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.703 |
KLI76212.1 | pyrB | AAW28_03300 | AAW28_04855 | Uric acid permease PucJ; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aspartate carbamoyltransferase catalytic subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.716 |
KLI76212.1 | pyrC | AAW28_03300 | AAW28_04850 | Uric acid permease PucJ; Derived by automated computational analysis using gene prediction method: Protein Homology. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.712 |
KLI76212.1 | pyrE | AAW28_03300 | AAW28_04825 | Uric acid permease PucJ; Derived by automated computational analysis using gene prediction method: Protein Homology. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.675 |
KLI76212.1 | pyrF | AAW28_03300 | AAW28_04830 | Uric acid permease PucJ; Derived by automated computational analysis using gene prediction method: Protein Homology. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.684 |
KLI76212.1 | pyrR | AAW28_03300 | AAW28_04865 | Uric acid permease PucJ; Derived by automated computational analysis using gene prediction method: Protein Homology. | Uracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant; Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily. | 0.716 |
KLI76212.1 | xpt | AAW28_03300 | AAW28_03295 | Uric acid permease PucJ; Derived by automated computational analysis using gene prediction method: Protein Homology. | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.993 |
KLI76213.1 | KLI76212.1 | AAW28_03305 | AAW28_03300 | Phosphoribosylaminoimidazole carboxylase; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate. Belongs to the PurK/PurT family. | Uric acid permease PucJ; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.820 |
KLI76213.1 | KLI76214.1 | AAW28_03305 | AAW28_03310 | Phosphoribosylaminoimidazole carboxylase; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate. Belongs to the PurK/PurT family. | Adenylosuccinate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.875 |
KLI76213.1 | carA | AAW28_03305 | AAW28_04845 | Phosphoribosylaminoimidazole carboxylase; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate. Belongs to the PurK/PurT family. | Carbamoyl phosphate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarA family. | 0.481 |
KLI76213.1 | guaA | AAW28_03305 | AAW28_01830 | Phosphoribosylaminoimidazole carboxylase; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate. Belongs to the PurK/PurT family. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.667 |
KLI76213.1 | xpt | AAW28_03305 | AAW28_03295 | Phosphoribosylaminoimidazole carboxylase; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate. Belongs to the PurK/PurT family. | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.884 |
KLI76214.1 | KLI76212.1 | AAW28_03310 | AAW28_03300 | Adenylosuccinate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Uric acid permease PucJ; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.675 |
KLI76214.1 | KLI76213.1 | AAW28_03310 | AAW28_03305 | Adenylosuccinate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylaminoimidazole carboxylase; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate. Belongs to the PurK/PurT family. | 0.875 |
KLI76214.1 | carA | AAW28_03310 | AAW28_04845 | Adenylosuccinate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Carbamoyl phosphate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarA family. | 0.462 |
KLI76214.1 | guaA | AAW28_03310 | AAW28_01830 | Adenylosuccinate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.984 |
KLI76214.1 | pyrB | AAW28_03310 | AAW28_04855 | Adenylosuccinate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Aspartate carbamoyltransferase catalytic subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.464 |