STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KLI76039.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (401 aa)    
Predicted Functional Partners:
KLI76038.1
Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.996
KLI76037.1
DEAD/DEAH box helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.988
KLI76893.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.984
KLI76040.1
Integrase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 'phage' integrase family.
 
   
 0.871
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
   0.634
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
   
 
 0.592
KLI76249.1
ATP synthase F0F1 subunit B; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.573
KLI75834.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.561
KLI76050.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
0.489
dnaJ
Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]
  
 
 0.442
Your Current Organism:
Lactobacillus casei
NCBI taxonomy Id: 1582
Other names: ATCC 393, BCRC 10697, Bacillus a, Bacillus casei a, Bacterium casei a, CCRC 10697, CCRC:10697, CECT 475, CIP 103137, Caseobacterium vulgare, DSM 20011, IAM 12473, IFO 15883, KCTC 3109, L. casei, LMG 6904, LMG:6904, Lactobacillus casei subsp. casei, Lactobacillus sp. NCIM 2363, Lactobacillus sp. NCIM 2732, Lactobacillus sp. T2, Lactobacillus sp. T20, Lactobacterium casei, NBRC 15883, NCDO 161, NCIMB 11970, NCTC 13641, Streptobacterium casei, strain Hucker03, strain Orla-Jensen 7, strain OrlandL-323, strain Tittsler303
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