STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KLI74576.1MerR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (144 aa)    
Predicted Functional Partners:
dnaJ
Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]
  
 
 0.801
KLI74911.1
Cell division protein FtsK; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FtsK/SpoIIIE/SftA family.
     
 0.749
KLI74798.1
Cell division protein FtsK; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.749
KLI76676.1
Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.657
KLI74579.1
Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family.
  
 
 0.657
sigA
RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
  
 
 0.643
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.624
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 0.585
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
   
 
 0.567
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.542
Your Current Organism:
Lactobacillus casei
NCBI taxonomy Id: 1582
Other names: ATCC 393, BCRC 10697, Bacillus a, Bacillus casei a, Bacterium casei a, CCRC 10697, CCRC:10697, CECT 475, CIP 103137, Caseobacterium vulgare, DSM 20011, IAM 12473, IFO 15883, KCTC 3109, L. casei, LMG 6904, LMG:6904, Lactobacillus casei subsp. casei, Lactobacillus sp. NCIM 2363, Lactobacillus sp. NCIM 2732, Lactobacillus sp. T2, Lactobacillus sp. T20, Lactobacterium casei, NBRC 15883, NCDO 161, NCIMB 11970, NCTC 13641, Streptobacterium casei, strain Hucker03, strain Orla-Jensen 7, strain OrlandL-323, strain Tittsler303
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