STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KLI74604.1Choloylglycine hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (338 aa)    
Predicted Functional Partners:
KLI76074.1
Thioredoxin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.781
hslO
Molecular chaperone Hsp33; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
     
 0.745
hslV
ATP-dependent protease; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
     
 0.733
comA
Peptide ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.698
dnaJ
Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]
     
 0.628
KLI75682.1
PTS fructose transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.582
KLI74605.1
ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.519
clpP
Clp protease; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
      
 0.503
KLI75304.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.503
KLI75684.1
Oligohyaluronate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.440
Your Current Organism:
Lactobacillus casei
NCBI taxonomy Id: 1582
Other names: ATCC 393, BCRC 10697, Bacillus a, Bacillus casei a, Bacterium casei a, CCRC 10697, CCRC:10697, CECT 475, CIP 103137, Caseobacterium vulgare, DSM 20011, IAM 12473, IFO 15883, KCTC 3109, L. casei, LMG 6904, LMG:6904, Lactobacillus casei subsp. casei, Lactobacillus sp. NCIM 2363, Lactobacillus sp. NCIM 2732, Lactobacillus sp. T2, Lactobacillus sp. T20, Lactobacterium casei, NBRC 15883, NCDO 161, NCIMB 11970, NCTC 13641, Streptobacterium casei, strain Hucker03, strain Orla-Jensen 7, strain OrlandL-323, strain Tittsler303
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