node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KRN22149.1 | carA-2 | IV69_GL000397 | IV69_GL001500 | Carbamoyl-phosphate synthase large subunit. | Carbamoyl-phosphate synthase small subunit; Belongs to the CarA family. | 0.999 |
KRN22149.1 | carB | IV69_GL000397 | IV69_GL001501 | Carbamoyl-phosphate synthase large subunit. | Carbamoyl-phosphate synthase large subunit; Belongs to the CarB family. | 0.922 |
KRN22149.1 | glnA | IV69_GL000397 | IV69_GL001299 | Carbamoyl-phosphate synthase large subunit. | L-glutamine synthetase. | 0.922 |
KRN22149.1 | purF | IV69_GL000397 | IV69_GL001092 | Carbamoyl-phosphate synthase large subunit. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.959 |
KRN22149.1 | purQ | IV69_GL000397 | IV69_GL001094 | Carbamoyl-phosphate synthase large subunit. | Phosphoribosylformylglycinamidine synthase domain-containing protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL an [...] | 0.922 |
KRN22149.1 | pyrB | IV69_GL000397 | IV69_GL001498 | Carbamoyl-phosphate synthase large subunit. | Aspartate carbamoyltransferase catalytic subunit; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.998 |
KRN22149.1 | pyrC | IV69_GL000397 | IV69_GL001499 | Carbamoyl-phosphate synthase large subunit. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.974 |
KRN22149.1 | pyrE | IV69_GL000397 | IV69_GL001504 | Carbamoyl-phosphate synthase large subunit. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.785 |
KRN22149.1 | pyrF | IV69_GL000397 | IV69_GL001503 | Carbamoyl-phosphate synthase large subunit. | Orotidine 5-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.768 |
KRN22149.1 | pyrP | IV69_GL000397 | IV69_GL001851 | Carbamoyl-phosphate synthase large subunit. | Uracil-xanthine permease. | 0.729 |
carA-2 | KRN22149.1 | IV69_GL001500 | IV69_GL000397 | Carbamoyl-phosphate synthase small subunit; Belongs to the CarA family. | Carbamoyl-phosphate synthase large subunit. | 0.999 |
carA-2 | carB | IV69_GL001500 | IV69_GL001501 | Carbamoyl-phosphate synthase small subunit; Belongs to the CarA family. | Carbamoyl-phosphate synthase large subunit; Belongs to the CarB family. | 0.999 |
carA-2 | glnA | IV69_GL001500 | IV69_GL001299 | Carbamoyl-phosphate synthase small subunit; Belongs to the CarA family. | L-glutamine synthetase. | 0.925 |
carA-2 | purF | IV69_GL001500 | IV69_GL001092 | Carbamoyl-phosphate synthase small subunit; Belongs to the CarA family. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.948 |
carA-2 | purQ | IV69_GL001500 | IV69_GL001094 | Carbamoyl-phosphate synthase small subunit; Belongs to the CarA family. | Phosphoribosylformylglycinamidine synthase domain-containing protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL an [...] | 0.943 |
carA-2 | pyrB | IV69_GL001500 | IV69_GL001498 | Carbamoyl-phosphate synthase small subunit; Belongs to the CarA family. | Aspartate carbamoyltransferase catalytic subunit; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
carA-2 | pyrC | IV69_GL001500 | IV69_GL001499 | Carbamoyl-phosphate synthase small subunit; Belongs to the CarA family. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.999 |
carA-2 | pyrE | IV69_GL001500 | IV69_GL001504 | Carbamoyl-phosphate synthase small subunit; Belongs to the CarA family. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.979 |
carA-2 | pyrF | IV69_GL001500 | IV69_GL001503 | Carbamoyl-phosphate synthase small subunit; Belongs to the CarA family. | Orotidine 5-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.982 |
carA-2 | pyrP | IV69_GL001500 | IV69_GL001851 | Carbamoyl-phosphate synthase small subunit; Belongs to the CarA family. | Uracil-xanthine permease. | 0.926 |