STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Fcan01_15203Wiskott-Aldrich syndrome protein. (765 aa)    
Predicted Functional Partners:
Fcan01_23409
Intersectin-2.
    
 0.979
Fcan01_16147
Intersectin-1.
    
 0.958
Fcan01_13413
WAS/WASL-interacting protein family member 2.
   
 0.909
Fcan01_06134
Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.
    
 0.886
Fcan01_02221
Actin-related protein 3; Belongs to the actin family.
    
 0.868
Fcan01_08073
Formin-binding protein 1-like.
   
 0.861
Fcan01_11996
Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
    
 0.831
Fcan01_08333
WD_REPEATS_REGION domain-containing protein.
    
 0.825
Fcan01_07840
Uncharacterized protein.
    
 0.807
Fcan01_03820
Uncharacterized protein.
    
 0.797
Your Current Organism:
Folsomia candida
NCBI taxonomy Id: 158441
Other names: F. candida
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.