STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Fcan01_13901Enkurin domain-containing protein 1. (520 aa)    
Predicted Functional Partners:
Fen1
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
   
 0.950
Fcan01_09358
DNA ligase.
  
 0.928
Fcan01_28373
DNA-(apurinic or apyrimidinic site) lyase; Belongs to the DNA repair enzymes AP/ExoA family.
    
 0.888
Fcan01_24746
DNA ligase 4; Belongs to the ATP-dependent DNA ligase family.
  
 0.886
Fcan01_22476
DNA repair protein XRCC1.
   
 0.881
Fcan01_22475
DNA repair protein XRCC1.
   
 0.881
Fcan01_18534
Bifunctional polynucleotide phosphatase/kinase.
    
 0.879
Fcan01_13663
X-ray repair cross-complementing protein 6.
    
 0.843
Fcan01_14192
DNA polymerase delta catalytic subunit.
  
 0.767
Fcan01_09157
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
    
 0.755
Your Current Organism:
Folsomia candida
NCBI taxonomy Id: 158441
Other names: F. candida
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.