STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Fcan01_13444Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (694 aa)    
Predicted Functional Partners:
Fcan01_04574
Nibrin.
    
 0.999
Fcan01_07802
BRCA1-associated RING domain protein 1.
   
 0.998
Fcan01_05359
Protein BREAST CANCER SUSCEPTIBILITY 1.
   
 0.978
Fcan01_03128
Non-specific serine/threonine protein kinase.
   
 0.978
Fcan01_13663
X-ray repair cross-complementing protein 6.
   
 0.970
Fen1
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
  
 0.968
Fcan01_08368
DNA repair protein RAD50.
  
 0.965
Fcan01_14305
Serine/threonine-protein kinase atr.
   
 0.963
Fcan01_07623
Bloom syndrome protein.
  
 0.954
Fcan01_17465
DNA repair protein RAD50.
  
 0.948
Your Current Organism:
Folsomia candida
NCBI taxonomy Id: 158441
Other names: F. candida
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.