STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Fcan01_03975Ubiquitin-protein ligase E3C. (1019 aa)    
Predicted Functional Partners:
Fcan01_00594
HECT domain-containing protein.
   
 
0.835
Fcan01_02744
Polyubiquitin.
   
 0.668
Fcan01_13100
MPN domain-containing protein.
    
 
 0.643
Fcan01_07849
OTU domain-containing protein 3.
      
 0.606
Fcan01_26716
Ubiquitin-conjugating enzyme E2 2; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.566
Fcan01_23560
Putative asparagine--tRNA ligase, mitochondrial.
      
 0.557
Fcan01_14413
Metal tolerance protein 9.
      
 0.557
Fcan01_28227
E3 ubiquitin-protein ligase listerin.
   
 0.543
Fcan01_12659
26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family.
    
 
 0.541
Fcan01_02087
E3 ubiquitin-protein ligase MARCH6.
      
 0.532
Your Current Organism:
Folsomia candida
NCBI taxonomy Id: 158441
Other names: F. candida
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.