STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Fcan01_03854Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (143 aa)    
Predicted Functional Partners:
Fcan01_03094
Histone H2B type 3-A; Belongs to the histone H2B family.
  
 0.918
Fcan01_13219
Histone H3; Belongs to the histone H3 family.
 
 
 0.891
Fcan01_18527
Histone H1.
   
 0.885
Fcan01_04056
Histone H2A; Belongs to the histone H2A family.
   
 0.865
Fcan01_21649
Histone acetyltransferase type B catalytic subunit.
    
 0.851
Fcan01_08992
Histone H1.
   
 0.839
Fcan01_04644
Lysine-specific demethylase 6A.
    
 0.796
Fcan01_06010
Histone acetyltransferase KAT2B.
    
 0.790
Fcan01_15243
Histone chaperone asf1.
    
 
 0.747
Fcan01_05281
Retinoblastoma-binding protein 5.
    
 0.746
Your Current Organism:
Folsomia candida
NCBI taxonomy Id: 158441
Other names: F. candida
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.