Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
tymsThymidylate synthetase. (321 aa)    
Predicted Functional Partners:
dhfr
Dihydrofolate reductase.
 
 
 0.999
tk1
Thymidine kinase 1.
  
 
 0.998
LOC114857630
Dihydrofolate reductase-like.
 
 
 0.998
dut
Deoxyuridine triphosphatase.
  
 0.995
dtymk
Deoxythymidylate kinase.
  
 
 0.993
dctd
dCMP deaminase.
  
 
 0.992
shmt1
Serine hydroxymethyltransferase 1.
  
 
 0.991
shmt2
Serine hydroxymethyltransferase 2.
  
 
 0.991
tk2
Thymidine kinase 2.
  
 
 0.989
mthfd2l
Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like.
  
 
 0.988
Your Current Organism:
Betta splendens
NCBI taxonomy Id: 158456
Other names: B. splendens, Siamese fighting fish
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