Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cul4aCullin 4A. (767 aa)    
Predicted Functional Partners:
ddb1
Damage specific DNA binding protein 1.
   
 0.995
ddb2
Damage specific DNA binding protein 2.
    
 0.985
dtl
Denticleless E3 ubiquitin protein ligase homolog.
    
 0.980
dcaf11
DDB1 and CUL4 associated factor 11.
    
 0.980
ercc8
ERCC excision repair 8, CSA ubiquitin ligase complex subunit.
    
 0.978
crbn
Cereblon.
    
 0.978
cops5
COP9 signalosome subunit 5.
    
 0.971
cops4
COP9 signalosome subunit 4.
    
 0.970
LOC114860326
E3 ubiquitin-protein ligase RBX1.
    
 0.970
wdtc1
WD and tetratricopeptide repeats 1.
    
 0.969
Your Current Organism:
Betta splendens
NCBI taxonomy Id: 158456
Other names: B. splendens, Siamese fighting fish
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