Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
nedd4NEDD4 E3 ubiquitin protein ligase. (876 aa)    
Predicted Functional Partners:
dlg3
Discs large MAGUK scaffold protein 3.
    
 0.929
rps27a
Ribosomal protein S27a.
    
  0.919
ndfip2
Nedd4 family interacting protein 2.
    
 
 0.919
LOC114869045
Angiomotin-like.
    
 0.918
ENSBSLP00000037601
Ubiquitin B.
    
 0.905
nedd4l
NEDD4 like E3 ubiquitin protein ligase.
  
  
 
0.901
sgk2
Serum/glucocorticoid regulated kinase 2.
    
 0.875
SGK1
Serum/glucocorticoid regulated kinase 1.
    
 0.875
LOC114865228
Serine/threonine-protein kinase Sgk1-like.
    
 0.875
egfr
Epidermal growth factor receptor.
    
 0.873
Your Current Organism:
Betta splendens
NCBI taxonomy Id: 158456
Other names: B. splendens, Siamese fighting fish
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