Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rwdd4RWD domain containing 4. (186 aa)    
Predicted Functional Partners:
drg2
Developmentally regulated GTP binding protein 2.
   
 0.955
drg1
Developmentally regulated GTP binding protein 1.
   
 0.935
znf330
Zinc finger protein 330.
   
   0.880
gcn1
GCN1 activator of EIF2AK4.
    
 
 0.798
esf1
ESF1 nucleolar pre-rRNA processing protein homolog.
   
   0.791
LOC114869525
High affinity cationic amino acid transporter 1-like.
      
 0.657
map3k4
Mitogen-activated protein kinase kinase kinase 4.
    
   0.646
zc3h15
Zinc finger CCCH-type containing 15.
   
 
 0.618
rwdd1
RWD domain containing 1.
   
  
 0.580
denr
Density regulated re-initiation and release factor.
   
    0.546
Your Current Organism:
Betta splendens
NCBI taxonomy Id: 158456
Other names: B. splendens, Siamese fighting fish
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