Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
restRE1 silencing transcription factor. (914 aa)    
Predicted Functional Partners:
kdm1a
Lysine demethylase 1A.
    
 0.979
rcor2
REST corepressor 2.
    
 0.961
rcor3
REST corepressor 3.
    
 0.961
LOC114865037
F-box/WD repeat-containing protein 11.
    
 0.916
HDAC2
Histone deacetylase 2.
    
 0.841
LOC114865711
Probable histone deacetylase 1-B.
    
 0.819
LOC114848179
Probable histone deacetylase 1-B.
    
 0.819
hdac8
Histone deacetylase 8.
    
 0.806
NR0B1
Nuclear receptor subfamily 0 group B member 1-like.
    
  0.795
mdm2
MDM2 proto-oncogene.
    
   0.782
Your Current Organism:
Betta splendens
NCBI taxonomy Id: 158456
Other names: B. splendens, Siamese fighting fish
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.