STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sos1SOS Ras/Rac guanine nucleotide exchange factor 1. (1313 aa)    
Predicted Functional Partners:
grb2
Growth factor receptor bound protein 2.
   
 0.989
SHC3
SHC adaptor protein 3.
    
 0.935
shc1
SHC adaptor protein 1.
    
 0.935
LOC114853312
Melanoma receptor tyrosine-protein kinase-like.
    
 0.934
egfr
Epidermal growth factor receptor.
    
 0.934
hras
HRas proto-oncogene, GTPase.
   
 0.918
ptpn11
Protein tyrosine phosphatase non-receptor type 11.
    
 0.907
LOC114858768
Tyrosine-protein phosphatase non-receptor type 11-like.
    
 0.907
ptpn6
Protein tyrosine phosphatase non-receptor type 6.
    
 0.907
mras
Muscle RAS oncogene homolog.
    
 0.892
Your Current Organism:
Betta splendens
NCBI taxonomy Id: 158456
Other names: B. splendens, Siamese fighting fish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.