STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC114866632Probable E3 ubiquitin-protein ligase HERC1. (4814 aa)    
Predicted Functional Partners:
rnf8
Ring finger protein 8.
   
 0.868
UBE3A
Ubiquitin-protein ligase E3A.
   
0.762
brca1
BRCA1 DNA repair associated.
    
 0.746
LOC114846828
ranBP2-like and GRIP domain-containing protein 3.
   
 0.735
LOC114854060
Ubiquitin-protein ligase E3A-like.
   
0.729
bard1
BRCA1 associated RING domain 1.
   
 0.716
pias4
Protein inhibitor of activated STAT 4.
    
 0.712
ENSBSLP00000037601
Ubiquitin B.
    
 0.711
LOC114862624
Ubiquitin-conjugating enzyme E2 N-like.
    
  0.705
ube2n
Ubiquitin conjugating enzyme E2 N.
    
  0.705
Your Current Organism:
Betta splendens
NCBI taxonomy Id: 158456
Other names: B. splendens, Siamese fighting fish
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.