STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
krasKRAS proto-oncogene, GTPase. (189 aa)    
Predicted Functional Partners:
nf1
Neurofibromin 1.
    
 0.950
LOC114845646
Serine/threonine-protein kinase A-Raf-like.
  
 0.944
rasa1
RAS p21 protein activator 1.
   
 0.941
rassf5
Ras association domain family member 5.
    
 0.936
raf1
Raf-1 proto-oncogene, serine/threonine kinase.
  
 0.930
braf
B-Raf proto-oncogene, serine/threonine kinase.
  
 0.930
plce1
Phospholipase C epsilon 1.
    
 0.924
ralbp1
ralA binding protein 1.
    
 0.921
LOC114849151
Afadin-like.
    
 0.918
LOC114853447
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform-like.
   
 0.904
Your Current Organism:
Betta splendens
NCBI taxonomy Id: 158456
Other names: B. splendens, Siamese fighting fish
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.