PTEN protein (Betta splendens) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

PTEN

annotation not available (410 aa)

Predicted Functional Partners:

LOC114853447

0.884

pik3cd

0.884

pik3cb

0.884

LOC114844354

0.884

usp7

0.879

LOC114844064

0.878

LOC114854785

0.878

LOC114861410

0.878

pik3cg

0.874

pik3c3

0.873

Your Current Organism:

Betta splendens

NCBI taxonomy Id: 158456
Other names: B. splendens, Siamese fighting fish

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC114844064	LOC114844354	ENSBSLP00000009880	ENSBSLP00000050697	Phosphatidylinositol 3-kinase regulatory subunit gamma-like.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform.	0.938
LOC114844064	LOC114853447	ENSBSLP00000009880	ENSBSLP00000004487	Phosphatidylinositol 3-kinase regulatory subunit gamma-like.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform-like.	0.938
LOC114844064	LOC114854785	ENSBSLP00000009880	ENSBSLP00000022403	Phosphatidylinositol 3-kinase regulatory subunit gamma-like.	Phosphatidylinositol 3-kinase regulatory subunit gamma-like.	0.844
LOC114844064	LOC114861410	ENSBSLP00000009880	ENSBSLP00000039824	Phosphatidylinositol 3-kinase regulatory subunit gamma-like.	Phosphatidylinositol 3-kinase regulatory subunit alpha-like.	0.841
LOC114844064	PTEN	ENSBSLP00000009880	ENSBSLP00000045802	Phosphatidylinositol 3-kinase regulatory subunit gamma-like.	annotation not available	0.878
LOC114844064	pik3c3	ENSBSLP00000009880	ENSBSLP00000015606	Phosphatidylinositol 3-kinase regulatory subunit gamma-like.	Phosphatidylinositol 3-kinase catalytic subunit type 3.	0.667
LOC114844064	pik3cb	ENSBSLP00000009880	ENSBSLP00000030169	Phosphatidylinositol 3-kinase regulatory subunit gamma-like.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta.	0.938
LOC114844064	pik3cd	ENSBSLP00000009880	ENSBSLP00000016821	Phosphatidylinositol 3-kinase regulatory subunit gamma-like.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta.	0.938
LOC114844064	pik3cg	ENSBSLP00000009880	ENSBSLP00000042175	Phosphatidylinositol 3-kinase regulatory subunit gamma-like.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma.	0.791
LOC114844354	LOC114844064	ENSBSLP00000050697	ENSBSLP00000009880	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform.	Phosphatidylinositol 3-kinase regulatory subunit gamma-like.	0.938
LOC114844354	LOC114853447	ENSBSLP00000050697	ENSBSLP00000004487	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform-like.	0.839
LOC114844354	LOC114854785	ENSBSLP00000050697	ENSBSLP00000022403	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform.	Phosphatidylinositol 3-kinase regulatory subunit gamma-like.	0.938
LOC114844354	LOC114861410	ENSBSLP00000050697	ENSBSLP00000039824	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform.	Phosphatidylinositol 3-kinase regulatory subunit alpha-like.	0.938
LOC114844354	PTEN	ENSBSLP00000050697	ENSBSLP00000045802	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform.	annotation not available	0.884
LOC114844354	pik3c3	ENSBSLP00000050697	ENSBSLP00000015606	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform.	Phosphatidylinositol 3-kinase catalytic subunit type 3.	0.746
LOC114844354	pik3cb	ENSBSLP00000050697	ENSBSLP00000030169	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta.	0.841
LOC114844354	pik3cg	ENSBSLP00000050697	ENSBSLP00000042175	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma.	0.871
LOC114853447	LOC114844064	ENSBSLP00000004487	ENSBSLP00000009880	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform-like.	Phosphatidylinositol 3-kinase regulatory subunit gamma-like.	0.938
LOC114853447	LOC114844354	ENSBSLP00000004487	ENSBSLP00000050697	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform-like.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform.	0.839
LOC114853447	LOC114854785	ENSBSLP00000004487	ENSBSLP00000022403	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform-like.	Phosphatidylinositol 3-kinase regulatory subunit gamma-like.	0.938